Canavier CC. (1999). Sodium dynamics underlying burst firing and putative mechanisms for the regulation of the firing pattern in midbrain dopamine neurons: a computational approach. Journal of computational neuroscience. 6 [PubMed]

See more from authors: Canavier CC

References and models cited by this paper

Bayer VE, Pickel VM. (1991). GABA-labeled terminals form proportionally more synapses with dopaminergic neurons containing low densities of tyrosine hydroxylase-immunoreactivity in rat ventral tegmental area. Brain research. 559 [PubMed]

Bernheimer H, Birkmayer W, Hornykiewicz O, Jellinger K, Seitelberger F. (1973). Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. Journal of the neurological sciences. 20 [PubMed]

Bloom FE, Koob GF, Vaccarino FJ, Amalric M. (1987). Positive rein-forcement properties of drugs: Search for neural substrates Brain Reward Systems And Abuse.

Brozoski TJ, Brown RM, Rosvold HE, Goldman PS. (1979). Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science (New York, N.Y.). 205 [PubMed]

Cardozo DL, Bean BP. (1995). Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors. Journal of neurophysiology. 74 [PubMed]

Carter CJ. (1982). Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats. Neuropharmacology. 21 [PubMed]

Celada P, Paladini CA, Tepper JM. (1999). GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata. Neuroscience. 89 [PubMed]

Charlety PJ et al. (1991). Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate. Acta physiologica Scandinavica. 142 [PubMed]

Chergui K et al. (1994). Subthalamic nucleus modulates burst firing of nigral dopamine neurones via NMDA receptors. Neuroreport. 5 [PubMed]

Chergui K et al. (1993). Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo. The European journal of neuroscience. 5 [PubMed]

Chergui K, Engberg G, Svensson TH, Mathe JM. (1996). GABAB receptors modulate the firing pattern of dopamine neurons in the ventral tegmental area Soc Neurosci Abstr. 22

Chergui K, Nomikos GG, Mathé JM, Gonon F, Svensson TH. (1996). Burst stimulation of the medial forebrain bundle selectively increase Fos-like immunoreactivity in the limbic forebrain of the rat. Neuroscience. 72 [PubMed]

Christoffersen CL, Meltzer LT. (1995). Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors. Neuroscience. 67 [PubMed]

De Weer P, Rakowski RF. (1984). Current generated by backward-running electrogenic Na pump in squid giant axons. Nature. 309 [PubMed]

Engberg G, Kling-Petersen T, Nissbrandt H. (1993). GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra. Synapse (New York, N.Y.). 15 [PubMed]

Fleck MW, Henze DA, Barrionuevo G, Palmer AM. (1993). Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 13 [PubMed]

Freeman AS, Meltzer LT, Bunney BS. (1985). Firing properties of substantia nigra dopaminergic neurons in freely moving rats. Life sciences. 36 [PubMed]

Fujimura K, Matsuda Y. (1989). Autogenous oscillatory potentials in neurons of the guinea pig substantia nigra pars compacta in vitro. Neuroscience letters. 104 [PubMed]

Gariano RF, Groves PM. (1988). Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices. Brain research. 462 [PubMed]

Glitsch HG, Krahn T, Pusch H. (1989). The dependence of sodium pump current on internal Na concentration and membrane potential in cardioballs from sheep Purkinje fibres. Pflugers Archiv : European journal of physiology. 414 [PubMed]

Gonon FG. (1988). Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience. 24 [PubMed]

Grace AA, Bunney BS. (1984). The control of firing pattern in nigral dopamine neurons: burst firing. The Journal of neuroscience : the official journal of the Society for Neuroscience. 4 [PubMed]

Grace AA, Onn SP. (1989). Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. 9 [PubMed]

Gu X, Blatz AL, German DC. (1992). Subtypes of substantia nigra dopaminergic neurons revealed by apamin: autoradiographic and electrophysiological studies. Brain research bulletin. 28 [PubMed]

Hairer E, Wanner G. (1991). Solving Ordinary Differential Equations II: Stiff and Differential-Algebraic Problems Springer Series In Computational Mathematics.

Hines M. (1993). NEURON--a program for simulation of nerve equations. Neural Systems: Analysis And Modeling.

Häusser M, Stuart G, Racca C, Sakmann B. (1995). Axonal initiation and active dendritic propagation of action potentials in substantia nigra neurons. Neuron. 15 [PubMed]

Hökfelt T, Everitt BJ, Theodorsson-Norheim E, Goldstein M. (1984). Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons. The Journal of comparative neurology. 222 [PubMed]

Hökfelt T et al. (1980). A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: evidence from immunohistochemistry combined with retrograde tracing. Neuroscience. 5 [PubMed]

Ip NY, Zigmond RE. (1984). Pattern of presynaptic nerve activity can determine the type of neurotransmitter regulating a postsynaptic event. Nature. 311 [PubMed]

Jansen KL, Faull RL, Storey P, Leslie RA. (1993). Loss of sigma binding sites in the CA1 area of the anterior hippocampus in Alzheimer's disease correlates with CA1 pyramidal cell loss. Brain research. 623 [PubMed]

Johnson SW, North RA. (1992). Two types of neurone in the rat ventral tegmental area and their synaptic inputs. The Journal of physiology. 450 [PubMed]

Johnson SW, Seutin V, North RA. (1992). Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science (New York, N.Y.). 258 [PubMed]

Johnson SW, Yn WU, Cameron W. (1996). Effect of baclofen on NMDA-mediated synaptic responses in rat midbrain dopamine neuron in vitro Soc Neurosci Abstr. 22

Johnston D, Wu SMS. (1995). Foundations of Cellular Neurophysiology with simulations and illustrations by Richard Gray Foundations of Cellular Neurophysiology.

Juraska JM, Wilson CJ, Groves PM. (1977). The substantia nigra of the rat: a Golgi study. The Journal of comparative neurology. 172 [PubMed]

Kang Y, Kitai ST. (1993). A whole cell patch-clamp study on the pacemaker potential in dopaminergic neurons of rat substantia nigra compacta. Neuroscience research. 18 [PubMed]

Kushmerick MJ, Podolsky RJ. (1969). Ionic mobility in muscle cells. Science (New York, N.Y.). 166 [PubMed]

Lacey MG, Mercuri NB, North RA. (1988). On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones. The Journal of physiology. 401 [PubMed]

Li YX, Bertram R, Rinzel J. (1996). Modeling N-methyl-D-aspartate-induced bursting in dopamine neurons. Neuroscience. 71 [PubMed]

Ljungberg T, Apicella P, Schultz W. (1992). Responses of monkey dopamine neurons during learning of behavioral reactions. Journal of neurophysiology. 67 [PubMed]

Marder E, Abbott LF. (1995). Theory in motion. Current opinion in neurobiology. 5 [PubMed]

Mayer ML, Westbrook GL. (1987). Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. The Journal of physiology. 394 [PubMed]

Mercuri NB, Bonci A, Calabresi P, Stefani A, Bernardi G. (1995). Properties of the hyperpolarization-activated cation current Ih in rat midbrain dopaminergic neurons. The European journal of neuroscience. 7 [PubMed]

Mercuri NB et al. (1994). Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones. British journal of pharmacology. 113 [PubMed]

Mercuri NB, Stratta F, Calabresi P, Bernardi G. (1992). A voltage-clamp analysis of NMDA-induced responses on dopaminergic neurons of the rat substantia nigra zona compacta and ventral tegmental area. Brain research. 593 [PubMed]

Mereu G, Costa E, Armstrong DM, Vicini S. (1991). Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. 11 [PubMed]

Mereu G et al. (1997). Spontaneous bursting activity of dopaminergic neurons in midbrain slices from immature rats: role of N-methyl-D-aspartate receptors. Neuroscience. 77 [PubMed]

Nakao M, Gadsby DC. (1989). [Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytes. The Journal of general physiology. 94 [PubMed]

Nedergaard S, Flatman JA, Engberg I. (1993). Nifedipine- and omega-conotoxin-sensitive Ca2+ conductances in guinea-pig substantia nigra pars compacta neurones. The Journal of physiology. 466 [PubMed]

O'Callaghan JF, Jarolimek W, Lewen A, Misgeld U. (1996). (-)-Baclofen-induced and constitutively active inwardly rectifying potassium conductances in cultured rat midbrain neurons. Pflugers Archiv : European journal of physiology. 433 [PubMed]

Overton P, Clark D. (1992). Iontophoretically administered drugs acting at the N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat. Synapse (New York, N.Y.). 10 [PubMed]

Ping HX, Shepard PD. (1996). Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons. Neuroreport. 7 [PubMed]

Preston RJ, McCrea RA, Chang HT, Kitai ST. (1981). Anatomy and physiology of substantia nigra and retrorubral neurons studied by extra- and intracellular recording and by horseradish peroxidase labeling. Neuroscience. 6 [PubMed]

Pytkowicz RM. (1979). Activity Coefficients in Electrolyte Solutions .

Ribak CE, Vaughn JE, Roberts E. (1980). GABAergic nerve terminals decrease in the substantia nigra following hemitransections of the striatonigral and pallidonigral pathways. Brain research. 192 [PubMed]

Rinzel J, Ermentrout GB. (1989). Analysis of neuronal excitability and oscillations Methods In Neuronal Modeling: From Synapses To Networks.

Rinzel J, Wang XJ. (1995). Oscillatory and bursting properties of neurons The Handbook Of Brain Theory And Neural Networks.

Robledo P, Féger J. (1990). Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data. Brain research. 518 [PubMed]

Romo R et al. (1995). Reward-related signals carried by dopamine neurons Models Of Information Processing In The Basal Ganglia. 12

Sanghera MK, Trulson ME, German DC. (1984). Electrophysiological properties of mouse dopamine neurons: in vivo and in vitro studies. Neuroscience. 12 [PubMed]

Scarnati E, Proia A, Campana E, Pacitti C. (1986). A microiontophoretic study on the nature of the putative synaptic neurotransmitter involved in the pedunculopontine-substantia nigra pars compacta excitatory pathway of the rat. Experimental brain research. 62 [PubMed]

Sesack SR, Pickel VM. (1992). Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. The Journal of comparative neurology. 320 [PubMed]

Seutin V, Johnson SW. (1997). Bicuculline methiodide potenti-ates NMDA-dependent burst firing by blocking apamin-sensitive Ca 2 C-activated KC currents in rat dopamine neurons. Soc Neurosci Abstr. 23

Seutin V, Johnson SW, North RA. (1993). Apamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons. Brain research. 630 [PubMed]

Seutin V, Johnson SW, North RA. (1993). Transmitter regulation of mesencephalic dopamine cells Limbic Motor Circuits And Neuropsychiatry. 3

Seutin V, Johnson SW, North RA. (1994). Effect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons. Neuroscience. 58 [PubMed]

Seutin V, Shen KZ, North RA, Johnson SW. (1996). Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons. Neuroscience. 71 [PubMed]

Shepard PD. (1993). The cellular basis of conditional bursting in mesencephalic dopamine-containing neurons Schizophren Res. 9

Shepard PD, Bunney BS. (1988). Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro. Brain research. 463 [PubMed]

Silva NL, Pechura CM, Barker JL. (1990). Postnatal rat nigrostriatal dopaminergic neurons exhibit five types of potassium conductances. Journal of neurophysiology. 64 [PubMed]

Svensson TH, Tung CS. (1989). Local cooling of pre-frontal cortex induces pacemaker-like firing of dopamine neurons in rat ventral tegmental area in vivo. Acta physiologica Scandinavica. 136 [PubMed]

Tepper JM, Martin LP, Anderson DR. (1995). GABAA receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 15 [PubMed]

Tepper JM, Sawyer SF, Groves PM. (1987). Electrophysiologically identified nigral dopaminergic neurons intracellularly labeled with HRP: light-microscopic analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 7 [PubMed]

Tong ZY, Overton PG, Clark D. (1996). Stimulation of the prefrontal cortex in the rat induces patterns of activity in midbrain dopaminergic neurons which resemble natural burst events. Synapse (New York, N.Y.). 22 [PubMed]

Walaas I, Fonnum F. (1980). Biochemical evidence for gamma-aminobutyrate containing fibres from the nucleus accumbens to the substantia nigra and ventral tegmental area in the rat. Neuroscience. 5 [PubMed]

Wang T, French ED. (1993). Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons. Synapse (New York, N.Y.). 13 [PubMed]

Wang T, O'Connor WT, Ungerstedt U, French ED. (1994). N-methyl-D-aspartic acid biphasically regulates the biochemical and electrophysiological response of A10 dopamine neurons in the ventral tegmental area: in vivo microdialysis and in vitro electrophysiological studies. Brain research. 666 [PubMed]

Watts AE, Williams JT, Henderson G. (1996). Baclofen inhibition of the hyperpolarization-activated cation current, Ih, in rat substantia nigra zona compacta neurons may be secondary to potassium current activation. Journal of neurophysiology. 76 [PubMed]

Wilson CJ, Young SJ, Groves PM. (1977). Statistical properties of neuronal spike trains in the substantia nigra: cell types and their interactions. Brain research. 136 [PubMed]

Wu HQ, Schwarcz R, Shepard PD. (1994). Excitatory amino acid-induced excitation of dopamine-containing neurons in the rat substantia nigra: modulation by kynurenic acid. Synapse (New York, N.Y.). 16 [PubMed]

Wu YN, Johnson SW. (1996). Pharmacological characterization of inward current evoked by N-methyl-D-aspartate in dopamine neurons in the rat brain slice. The Journal of pharmacology and experimental therapeutics. 279 [PubMed]

Yung WH, Häusser MA, Jack JJ. (1991). Electrophysiology of dopaminergic and non-dopaminergic neurones of the guinea-pig substantia nigra pars compacta in vitro. The Journal of physiology. 436 [PubMed]

Zhang J, Chiodo LA, Freeman AS. (1994). Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra. The Journal of pharmacology and experimental therapeutics. 269 [PubMed]

References and models that cite this paper

Ashhad S, Narayanan R. (2013). Quantitative interactions between the A-type K+ current and inositol trisphosphate receptors regulate intraneuronal Ca2+ waves and synaptic plasticity. The Journal of physiology. 591 [PubMed]

Basak R, Narayanan R. (2018). Active dendrites regulate the spatiotemporal spread of signaling microdomains. PLoS computational biology. 14 [PubMed]

Ben-Shalom R et al. (2022). NeuroGPU: Accelerating multi-compartment, biophysically detailed neuron simulations on GPUs Journal of neuroscience methods. 366 [PubMed]

Canavier CC, Landry RS. (2006). An increase in AMPA and a decrease in SK conductance increase burst firing by different mechanisms in a model of a dopamine neuron in vivo. Journal of neurophysiology. 96 [PubMed]

Carnevale NT, Hines M. (2003). Personal Communication of NEURON bibliography .

Carnevale NT, Morse TM. (1996). Research reports that have used NEURON Web published citations at the NEURON website.

Hines ML, Carnevale NT. (2001). NEURON: a tool for neuroscientists. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 7 [PubMed]

Knowlton C, Kutterer S, Roeper J, Canavier CC. (2018). Calcium dynamics control K-ATP channel-mediated bursting in substantia nigra dopamine neurons: a combined experimental and modeling study. Journal of neurophysiology. 119 [PubMed]

Kole MH et al. (2008). Action potential generation requires a high sodium channel density in the axon initial segment. Nature neuroscience. 11 [PubMed]

Komendantov AO, Komendantova OG, Johnson SW, Canavier CC. (2004). A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons. Journal of neurophysiology. 91 [PubMed]

Komendantov AO, Trayanova NA, Tasker JG. (2007). Somato-dendritic mechanisms underlying the electrophysiological properties of hypothalamic magnocellular neuroendocrine cells: a multicompartmental model study. Journal of computational neuroscience. 23 [PubMed]

Kuznetsov AS, Kopell NJ, Wilson CJ. (2006). Transient high-frequency firing in a coupled-oscillator model of the mesencephalic dopaminergic neuron. Journal of neurophysiology. 95 [PubMed]

Narayanan R, Johnston D. (2010). The h current is a candidate mechanism for regulating the sliding modification threshold in a BCM-like synaptic learning rule. Journal of neurophysiology. 104 [PubMed]

Sundt D, Gamper N, Jaffe DB. (2015). Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study. Journal of neurophysiology. 114 [PubMed]

Yu N, Canavier CC. (2015). A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block. Journal of mathematical neuroscience. 5 [PubMed]

Zylbertal A, Kahan A, Ben-Shaul Y, Yarom Y, Wagner S. (2015). Prolonged Intracellular Na+ Dynamics Govern Electrical Activity in Accessory Olfactory Bulb Mitral Cells. PLoS biology. 13 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.