<StimulationSet>

    <!-- the injectionSite must match a regionLabel deefined in the morphology -->
   <!-- 20 Glu and Ca pulses / sec for 1 sec * 20 trains = 400 pulses -->

<!-- pulse 1 to produce 0.5 uM alone -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               50000          </onset>
        <duration>            15              </duration>
        <rate>                36            </rate>
        <period>              50             </period>
        <end>                 50020          </end>
</InjectionStim>

<!-- pulse 2 = half of pulse 1 -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               50050          </onset>
        <duration>            15              </duration>
        <rate>                18.0           </rate>
        <period>              50             </period>
        <end>                 50070          </end>
</InjectionStim>

<!-- pulse 3 = half of pulse 2  -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               50100          </onset>
        <duration>            15              </duration>
        <rate>                12.6           </rate>
        <period>              50             </period>
        <end>                 50120          </end>
</InjectionStim>

<!-- pulses 4-20 = half of pulse 3, faster injection to decrease stochasticity-->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               50150          </onset>
        <duration>            15              </duration>
        <rate>                6           </rate>
        <period>              50             </period>
        <end>                 50999          </end>
</InjectionStim>


<!--later bursts of Da - partial strength (2/3d) -->
<!-- pulse 1 to produce 0.5 uM alone -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               60000          </onset>
        <duration>            15              </duration>
        <rate>                24            </rate>
        <period>              50             </period>
        <end>                 60020          </end>
</InjectionStim>

<!-- pulse 2 = half of pulse 1 -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               60050          </onset>
        <duration>            15              </duration>
        <rate>                12.0           </rate>
        <period>              50             </period>
        <end>                 60070          </end>
</InjectionStim>

<!-- pulse 3 = half of pulse 2  -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               60100          </onset>
        <duration>            15              </duration>
        <rate>                8.4           </rate>
        <period>              50             </period>
        <end>                 60120          </end>
</InjectionStim>

<!-- pulses 4-20 = half of pulse 3, faster injection to decrease stochasticity-->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               60150          </onset>
        <duration>            15              </duration>
        <rate>                4           </rate>
        <period>              50             </period>
        <end>                 60999          </end>
</InjectionStim>

<!--even later bursts of Da - halfstrength -->
<!-- third and subsequent trains even smaller -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               70000          </onset>
        <duration>            15              </duration>
        <rate>                4.0            </rate>
        <period>              50             </period>
        <end>                 70999          </end>
</InjectionStim>

<!-- fourth and subsequent trains smaller still -->
<InjectionStim specieID="DaDbuf" injectionSite="sa1[0,8].pointA">
        <onset>               80000          </onset>
        <duration>            15              </duration>
        <rate>                2.0            </rate>
        <period>              50             </period>
        <end>                 80999          </end>
        <numTrains>           17             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>   
</InjectionStim>

<!-- basal ACh value prior to and after stim  -->
<InjectionStim specieID="ACh" injectionSite="dend:submembrane">
        <onset>               0          </onset>
        <duration>            50000      </duration>
        <rate>                2         </rate>
</InjectionStim>
<InjectionStim specieID="ACh" injectionSite="dend:submembrane">
        <onset>               250000          </onset>
        <duration>            200000      </duration>
        <rate>                2         </rate>
</InjectionStim>
<!-- basal ACh stim paused during Da stim-->
<InjectionStim specieID="ACh" injectionSite="dend:submembrane">
        <onset>               53200          </onset>
        <duration>            6800      </duration>
        <rate>                2         </rate>
        <period>              10000             </period>
        <end>                 250000          </end>
</InjectionStim>
<!-- burst during stim : Assume that ACh neurons can follow 20 Hz -->
<InjectionStim specieID="ACh" injectionSite="sa1[0,6].pointA">
        <onset>               50000          </onset>
        <duration>            15              </duration>
        <rate>                6.0           </rate>
        <period>              50             </period>
        <end>                 50999          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>  
</InjectionStim>

<!-- Should this stimulation be eliminated???-->
<InjectionStim specieID="ACh" injectionSite="dend:submembrane">
        <onset>               50000          </onset>
        <duration>            15              </duration>
        <rate>                30.0           </rate>
        <period>              50             </period>
        <end>                 50999          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>  
 </InjectionStim>

 <!-- rebound burst: develops more slowly -->
<InjectionStim specieID="ACh" injectionSite="sa1[0,6].pointA">
        <onset>               52400          </onset>
        <duration>            800            </duration>
        <rate>                0            </rate>
        <period>              900           </period>
        <end>                 53299          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9101          </interTrainInterval>  
</InjectionStim>

<!-- Train 1 -->
<InjectionStim specieID="GluGbuf" injectionSite="sa1[0,6].pointA">
        <onset>               50000          </onset>
        <duration>            5              </duration>
        <rate>                2.25           </rate>
        <period>              50             </period>
        <end>                 50999          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>   
</InjectionStim>

<InjectionStim specieID="Ca" injectionSite="sa1[0,6].pointA">
        <onset>               50000          </onset>
        <duration>            3              </duration>
        <rate>                312            </rate>
        <period>              50             </period>
        <end>                 50999          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>  
</InjectionStim>

<InjectionStim specieID="Ca" injectionSite="dend:submembrane">
        <onset>               50000          </onset>
        <duration>            3              </duration>
        <rate>                1560            </rate>
        <period>              50             </period>
        <end>                 50999          </end>
        <numTrains>           20             </numTrains>
        <interTrainInterval>  9001          </interTrainInterval>  
</InjectionStim>

</StimulationSet>