This model package provides NEURON codes associated with paper: Vasilkov V. A. and Tikidji-Hamburyan R. A.(2012) Accurate Detection of Interaural Time Differences by a Population of Slowly Integrating Neurons. Phys. Rev. Lett. 108, 138104. Scripts in this folder were used to produce Fig.3c of the paper. Any questions for implementing the model should be directed to Ruben Tikidji-Hamburyan (rtikid@lsuhsc.edu, ruben.tikidji.hamburyan@gmail.com) OR/AND Viacheslav Vasilkov (vasilkov.va@gmail.com) *************************************************************************** To run simulation: under Linux: $nrnivmodl $nrngui -nogui hh10000-X-X-X.hoc To get dat file: $python csv2dat.py hh10000-X-X-X.csv *************************************************************************** File description: README - this file hh10000-gsyngrad-scan11-step0.01.hoc hh10000-gsyngrad-scan55-step0.1.hoc hh10000-delaygrad-scan11-step0.01.hoc hh10000-delaygrad-scan55-step0.1.hoc hh10000-jitter-scan11-step0.01.hoc hh10000-jitter-scan55-step0.1.hoc hh10000-noisecur-scan11-step0.01.hoc hh10000-noisecur-scan55-step0.1.hoc every script produces a 'comma separated values' file(csv) with population-rate transfer function for 10000 Hodgkin-Huxley neurons model, with: gsyngrad - synaptic conductances gradients delaygrad - delay lines gradients jitter - jitter in pathways noisecur - neuron intrinsic noise current scan11 / scan55 means that population-rate transfer function was tested within [-1, 1]ms or [-5, 5]ms respectively. step - indicates ITD step for testing mesh in selected range. rgi.mod - mechanisms for noise current. For better performance, please use Ted Carnevale's InNp.mod for future versions. hhcell.hoc - template for standard Hodgkin-Huxley neuron model with noise current. WARNING: To use scripts with thread mode, one must include independent random number generator in this template . main.hoc - functions to run simulation iteratively and obtain population-rate transfer function. DON'T run this file. See Scripts above. csv2dat.py - simple python script, to convert csv to standard two columns dat file.