ModelDB: Models that contain CalC Calcium Calculator

Simulation Environment: CalC Calcium Calculator

Note: this list includes both models hosted here at ModelDB and models where have metadata and link to the sourcecode somewhere else. These may also be viewed separately; see the browse by simulator page.

Determinants of fast calcium dynamics in dendritic spines and dendrites (Cornelisse et al. 2007)
Ca2+ current versus Ca2+ channel cooperativity of exocytosis (Matveev et al. 2009)
Facilitation model based on bound Ca2+ (Matveev et al. 2006)
Facilitation through buffer saturation (Matveev et al. 2004)
New and corrected simulations of synaptic facilitation (Matveev et al. 2002)
Permeation and inactivation of CaV1.2 Ca2+ channels (Babich et al. 2007)
Stochastic automata network Markov model descriptors of coupled Ca2+ channels (Nguyen et al. 2005)
Transmitter release and Ca diffusion models (Yamada and Zucker 1992)

http://web.njit.edu/~matveev/calc.html
CalC ("Calcium Calculator") is a modeling tool for integrating the 3D reaction-diffusion problem (or the corresponding reduced 1D and 2D problems) arising in biophysical modeling of intracellular calcium dynamics. CalC simulates the entry of calcium into a volume through point-like channels, and its diffusion, buffering and binding to calcium receptors.

Top authors for CalC Calcium Calculator:

Matveev V (5)
Sherman A (4)
Zucker RS (3)
Bertram R (2)
Cornelisse LN (1)
van Elburg RA (1)
Meredith RM (1)
Yuste R (1)
Mansvelder HD (1)
Babich O (1)

Top concepts studied with CalC Calcium Calculator:

Calcium dynamics (7)
Facilitation (4)
Ion Channel Kinetics (2)
Synaptic Plasticity (1)
Markov-type model (1)

Top neurons studied with CalC Calcium Calculator:

Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell (1)

Top currents studied with CalC Calcium Calculator:

I Calcium (2)
I L high threshold (1)

Top references cited by these models:

Allbritton NL, Meyer T, Stryer L. (1992). Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science (New York, N.Y.). 258 (5)
Nowycky MC, Pinter MJ. (1993). Time courses of calcium and calcium-bound buffers following calcium influx in a model cell. Biophysical journal. 64 (4)
Sala F, Hernández-Cruz A. (1990). Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties. Biophysical journal. 57 (4)
Kits KS, de Vlieger TA, Kooi BW, Mansvelder HD. (1999). Diffusion barriers limit the effect of mobile calcium buffers on exocytosis of large dense cored vesicles. Biophysical journal. 76 (3)
Klingauf J, Neher E. (1997). Modeling buffered Ca2+ diffusion near the membrane: implications for secretion in neuroendocrine cells. Biophysical journal. 72 (3)