Anoxic depolarization, recovery: effect of brain regions and extracellular space (Hubel et al. 2016)


Hübel N, Andrew RD, Ullah G. (2016). Large extracellular space leads to neuronal susceptibility to ischemic injury in a Na+/K+ pumps-dependent manner. Journal of computational neuroscience. 40 [PubMed]

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References and models cited by this paper

Attwell D, Laughlin SB. (2001). An energy budget for signaling in the grey matter of the brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 21 [PubMed]

Barreto E, Cressman JR. (2011). Ion concentration dynamics as a mechanism for neuronal bursting. Journal of biological physics. 37 [PubMed]

Bazhenov M, Timofeev I, Steriade M, Sejnowski TJ. (2004). Potassium model for slow (2-3 Hz) in vivo neocortical paroxysmal oscillations. Journal of neurophysiology. 92 [PubMed]

Berthon B, Burgess GM, Capiod T, Claret M, Poggioli J. (1983). Mechanism of action of noradrenaline on the sodium-potassium pump in isolated rat liver cells. The Journal of physiology. 341 [PubMed]

Blanco G. (2005). Na,K-ATPase subunit heterogeneity as a mechanism for tissue-specific ion regulation. Seminars in nephrology. 25 [PubMed]

Brisson CD, Andrew RD. (2012). A neuronal population in hypothalamus that dramatically resists acute ischemic injury compared to neocortex. Journal of neurophysiology. 108 [PubMed]

Brisson CD, Hsieh YT, Kim D, Jin AY, Andrew RD. (2014). Brainstem neurons survive the identical ischemic stress that kills higher neurons: insight to the persistent vegetative state. PloS one. 9 [PubMed]

Brisson CD, Lukewich MK, Andrew RD. (2013). A distinct boundary between the higher brain's susceptibility to ischemia and the lower brain's resistance. PloS one. 8 [PubMed]

Centonze D et al. (2001). Ionic mechanisms underlying differential vulnerability to ischemia in striatal neurons. Progress in neurobiology. 63 [PubMed]

Collins CE, Airey DC, Young NA, Leitch DB, Kaas JH. (2010). Neuron densities vary across and within cortical areas in primates. Proceedings of the National Academy of Sciences of the United States of America. 107 [PubMed]

Cressman JR, Ullah G, Ziburkus J, Schiff SJ, Barreto E. (2009). The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. Journal of computational neuroscience. 26 [PubMed]

Cressman JR, Ullah G, Ziburkus J, Schiff SJ, Barreto E. (2011). Erratum J Comput Neurosci.. 30(3)

Dahlem MA, Schumacher J, Hübel N. (2014). Linking a genetic defect in migraine to spreading depression in a computational model. PeerJ. 2 [PubMed]

Dijkhuizen RM et al. (1999). Correlation between tissue depolarizations and damage in focal ischemic rat brain. Brain research. 840 [PubMed]

Dobretsov M, Stimers JR. (2005). Neuronal function and alpha3 isoform of the Na/K-ATPase. Frontiers in bioscience : a journal and virtual library. 10 [PubMed]

Falini A et al. (1998). Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study. AJNR. American journal of neuroradiology. 19 [PubMed]

Fröhlich F, Bazhenov M. (2006). Coexistence of tonic firing and bursting in cortical neurons. Physical review. E, Statistical, nonlinear, and soft matter physics. 74 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology. 117 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. The Journal of physiology. 116 [PubMed]

HODGKIN AL, HUXLEY AF. (1952). The components of membrane conductance in the giant axon of Loligo. The Journal of physiology. 116 [PubMed]

HODGKIN AL, HUXLEY AF, KATZ B. (1952). Measurement of current-voltage relations in the membrane of the giant axon of Loligo. The Journal of physiology. 116 [PubMed]

Hansen AJ, Zeuthen T. (1981). Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta physiologica Scandinavica. 113 [PubMed]

Herculano-Houzel S, Lent R. (2005). Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM. (2004). ModelDB: A Database to Support Computational Neuroscience. Journal of computational neuroscience. 17 [PubMed]

Hodgkin AL. (1948). The local electric changes associated with repetitive action in a non-medullated axon. The Journal of physiology. 107 [PubMed]

Hoffmann U, Sukhotinsky I, Atalay YB, Eikermann-Haerter K, Ayata C. (2012). Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury. Experimental neurology. 238 [PubMed]

Hübel N, Dahlem MA. (2014). Dynamics from seconds to hours in Hodgkin-Huxley model with time-dependent ion concentrations and buffer reservoirs. PLoS computational biology. 10 [PubMed]

Hübel N, Schöll E, Dahlem MA. (2014). Bistable dynamics underlying excitability of ion homeostasis in neuron models. PLoS computational biology. 10 [PubMed]

Ingram J et al. (2014). Oxygen and seizure dynamics: I. Experiments. Journal of neurophysiology. 112 [PubMed]

Kager H, Wadman WJ, Somjen GG. (2000). Simulated seizures and spreading depression in a neuron model incorporating interstitial space and ion concentrations. Journal of neurophysiology. 84 [PubMed]

Kager H, Wadman WJ, Somjen GG. (2002). Conditions for the triggering of spreading depression studied with computer simulations. Journal of neurophysiology. 88 [PubMed]

Kager H, Wadman WJ, Somjen GG. (2007). Seizure-like afterdischarges simulated in a model neuron. Journal of computational neuroscience. 22 [PubMed]

Krishnan GP, Bazhenov M. (2011). Ionic dynamics mediate spontaneous termination of seizures and postictal depression state. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31 [PubMed]

Krizaj D, Rice ME, Wardle RA, Nicholson C. (1996). Water compartmentalization and extracellular tortuosity after osmotic changes in cerebellum of Trachemys scripta. The Journal of physiology. 492 ( Pt 3) [PubMed]

Luigetti M, Goldsberry GT, Cianfoni A. (2012). Brain MRI in global hypoxia-ischemia: a map of selective vulnerability. Acta neurologica Belgica. 112 [PubMed]

Mazel T, Simonová Z, Syková E. (1998). Diffusion heterogeneity and anisotropy in rat hippocampus. Neuroreport. 9 [PubMed]

McBain CJ, Traynelis SF, Dingledine R. (1990). Regional variation of extracellular space in the hippocampus. Science (New York, N.Y.). 249 [PubMed]

Mulet J, Mirasso CR. (1999). Numerical statistics of power dropouts based on the Lang-Kobayashi model. Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics. 59 [PubMed]

Murphy TH, Li P, Betts K, Liu R. (2008). Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28 [PubMed]

Rosenberg GA. (1999). Ischemic brain edema. Progress in cardiovascular diseases. 42 [PubMed]

Sawas AH, Gilbert JC. (1981). Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes. Biochemical pharmacology. 30 [PubMed]

Schüz A, Palm G. (1989). Density of neurons and synapses in the cerebral cortex of the mouse. The Journal of comparative neurology. 286 [PubMed]

Somjen GG. (2004). Ions in the brain: Normal function, seizures and stroke.

Sukhotinsky I et al. (2010). Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 30 [PubMed]

Timme M, Shandilya SG. (2011). Inferring network topology from complex dynamics New Journal of Physical. 13(1)

Ullah G, Schiff SJ. (2009). Tracking and control of neuronal Hodgkin-Huxley dynamics. Physical review. E, Statistical, nonlinear, and soft matter physics. 79 [PubMed]

Ullah G, Schiff SJ. (2010). Assimilating seizure dynamics. PLoS computational biology. 6 [PubMed]

Ullah G, Wei Y, Dahlem MA, Wechselberger M, Schiff SJ. (2015). The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization. PLoS computational biology. 11 [PubMed]

Wang XJ et al. (2009). AUTO-07P: continuation and bifurcation software for ordinary differential equations Available from: http:--cmvl.cs.

Wei Y, Ullah G, Ingram J, Schiff SJ. (2014). Oxygen and seizure dynamics: II. Computational modeling. Journal of neurophysiology. 112 [PubMed]

Wei Y, Ullah G, Schiff SJ. (2014). Unification of neuronal spikes, seizures, and spreading depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Xie L et al. (2013). Sleep drives metabolite clearance from the adult brain. Science (New York, N.Y.). 342 [PubMed]

Yao W, Huang H, Miura RM. (2011). A continuum neuronal model for the instigation and propagation of cortical spreading depression. Bulletin of mathematical biology. 73 [PubMed]

Zamecnik J et al. (2012). The extracellular matrix and diffusion barriers in focal cortical dysplasias. The European journal of neuroscience. 36 [PubMed]

Zandt BJ, ten Haken B, van Dijk JG, van Putten MJ. (2011). Neural dynamics during anoxia and the "wave of death". PloS one. 6 [PubMed]

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Hübel N, Hosseini-Zare MS, Žiburkus J, Ullah G. (2017). The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization. PLoS computational biology. 13 [PubMed]

Hübel N, Ullah G. (2016). Anions Govern Cell Volume: A Case Study of Relative Astrocytic and Neuronal Swelling in Spreading Depolarization. PloS one. 11 [PubMed]

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