/* Created by Language version: 6.2.0 */
/* NOT VECTORIZED */
#include <stdio.h>
#include <stdlib.h>
#include <math.h>
#include "scoplib_ansi.h"
#undef PI
#define nil 0
#include "md1redef.h"
#include "section.h"
#include "nrniv_mf.h"
#include "md2redef.h"
 
#if METHOD3
extern int _method3;
#endif

#if !NRNGPU
#undef exp
#define exp hoc_Exp
extern double hoc_Exp(double);
#endif
 
#define _threadargscomma_ /**/
#define _threadargs_ /**/
 
#define _threadargsprotocomma_ /**/
#define _threadargsproto_ /**/
 	/*SUPPRESS 761*/
	/*SUPPRESS 762*/
	/*SUPPRESS 763*/
	/*SUPPRESS 765*/
	 extern double *getarg();
 static double *_p; static Datum *_ppvar;
 
#define t nrn_threads->_t
#define dt nrn_threads->_dt
#define gbar _p[0]
#define gna _p[1]
#define minf _p[2]
#define hinf _p[3]
#define mtau _p[4]
#define htau _p[5]
#define m _p[6]
#define h _p[7]
#define ina _p[8]
#define ena _p[9]
#define Dm _p[10]
#define Dh _p[11]
#define _g _p[12]
#define _ion_ena	*_ppvar[0]._pval
#define _ion_ina	*_ppvar[1]._pval
#define _ion_dinadv	*_ppvar[2]._pval
 
#if MAC
#if !defined(v)
#define v _mlhv
#endif
#if !defined(h)
#define h _mlhh
#endif
#endif
 
#if defined(__cplusplus)
extern "C" {
#endif
 static int hoc_nrnpointerindex =  -1;
 /* external NEURON variables */
 extern double celsius;
 /* declaration of user functions */
 static void _hoc_myexp(void);
 static void _hoc_rates(void);
 static void _hoc_states(void);
 static void _hoc_trap0(void);
 static void _hoc_trates(void);
 static int _mechtype;
extern void _nrn_cacheloop_reg(int, int);
extern void hoc_register_prop_size(int, int, int);
extern void hoc_register_limits(int, HocParmLimits*);
extern void hoc_register_units(int, HocParmUnits*);
extern void nrn_promote(Prop*, int, int);
extern Memb_func* memb_func;
 extern void _nrn_setdata_reg(int, void(*)(Prop*));
 static void _setdata(Prop* _prop) {
 _p = _prop->param; _ppvar = _prop->dparam;
 }
 static void _hoc_setdata() {
 Prop *_prop, *hoc_getdata_range(int);
 _prop = hoc_getdata_range(_mechtype);
   _setdata(_prop);
 hoc_retpushx(1.);
}
 /* connect user functions to hoc names */
 static VoidFunc hoc_intfunc[] = {
 "setdata_na", _hoc_setdata,
 "myexp_na", _hoc_myexp,
 "rates_na", _hoc_rates,
 "states_na", _hoc_states,
 "trap0_na", _hoc_trap0,
 "trates_na", _hoc_trates,
 0, 0
};
#define myexp myexp_na
#define trap0 trap0_na
 extern double myexp( double );
 extern double trap0( double , double , double , double );
 /* declare global and static user variables */
#define Rg Rg_na
 double Rg = 0.0091;
#define Rd Rd_na
 double Rd = 0.024;
#define Rb Rb_na
 double Rb = 0.124;
#define Ra Ra_na
 double Ra = 0.182;
#define q10 q10_na
 double q10 = 2.3;
#define qinf qinf_na
 double qinf = 6.2;
#define qi qi_na
 double qi = 5;
#define qa qa_na
 double qa = 9;
#define tadj tadj_na
 double tadj = 0;
#define temp temp_na
 double temp = 23;
#define thinf thinf_na
 double thinf = -65;
#define thi2 thi2_na
 double thi2 = -75;
#define thi1 thi1_na
 double thi1 = -50;
#define tha tha_na
 double tha = -35;
#define usetable usetable_na
 double usetable = 1;
#define vshift vshift_na
 double vshift = -10;
#define vmax vmax_na
 double vmax = 100;
#define vmin vmin_na
 double vmin = -120;
 /* some parameters have upper and lower limits */
 static HocParmLimits _hoc_parm_limits[] = {
 "usetable_na", 0, 1,
 0,0,0
};
 static HocParmUnits _hoc_parm_units[] = {
 "vshift_na", "mV",
 "tha_na", "mV",
 "qa_na", "mV",
 "Ra_na", "/ms",
 "Rb_na", "/ms",
 "thi1_na", "mV",
 "thi2_na", "mV",
 "qi_na", "mV",
 "thinf_na", "mV",
 "qinf_na", "mV",
 "Rg_na", "/ms",
 "Rd_na", "/ms",
 "temp_na", "degC",
 "vmin_na", "mV",
 "vmax_na", "mV",
 "gbar_na", "pS/um2",
 "gna_na", "pS/um2",
 "mtau_na", "ms",
 "htau_na", "ms",
 0,0
};
 static double delta_t = 1;
 static double h0 = 0;
 static double m0 = 0;
 static double v = 0;
 /* connect global user variables to hoc */
 static DoubScal hoc_scdoub[] = {
 "vshift_na", &vshift_na,
 "tha_na", &tha_na,
 "qa_na", &qa_na,
 "Ra_na", &Ra_na,
 "Rb_na", &Rb_na,
 "thi1_na", &thi1_na,
 "thi2_na", &thi2_na,
 "qi_na", &qi_na,
 "thinf_na", &thinf_na,
 "qinf_na", &qinf_na,
 "Rg_na", &Rg_na,
 "Rd_na", &Rd_na,
 "temp_na", &temp_na,
 "q10_na", &q10_na,
 "vmin_na", &vmin_na,
 "vmax_na", &vmax_na,
 "tadj_na", &tadj_na,
 "usetable_na", &usetable_na,
 0,0
};
 static DoubVec hoc_vdoub[] = {
 0,0,0
};
 static double _sav_indep;
 static void nrn_alloc(Prop*);
static void  nrn_init(_NrnThread*, _Memb_list*, int);
static void nrn_state(_NrnThread*, _Memb_list*, int);
 static void nrn_cur(_NrnThread*, _Memb_list*, int);
static void  nrn_jacob(_NrnThread*, _Memb_list*, int);
 
static int _ode_count(int);
 /* connect range variables in _p that hoc is supposed to know about */
 static const char *_mechanism[] = {
 "6.2.0",
"na",
 "gbar_na",
 0,
 "gna_na",
 "minf_na",
 "hinf_na",
 "mtau_na",
 "htau_na",
 0,
 "m_na",
 "h_na",
 0,
 0};
 static Symbol* _na_sym;
 
extern Prop* need_memb(Symbol*);

static void nrn_alloc(Prop* _prop) {
	Prop *prop_ion;
	double *_p; Datum *_ppvar;
 	_p = nrn_prop_data_alloc(_mechtype, 13, _prop);
 	/*initialize range parameters*/
 	gbar = 1000;
 	_prop->param = _p;
 	_prop->param_size = 13;
 	_ppvar = nrn_prop_datum_alloc(_mechtype, 3, _prop);
 	_prop->dparam = _ppvar;
 	/*connect ionic variables to this model*/
 prop_ion = need_memb(_na_sym);
 nrn_promote(prop_ion, 0, 1);
 	_ppvar[0]._pval = &prop_ion->param[0]; /* ena */
 	_ppvar[1]._pval = &prop_ion->param[3]; /* ina */
 	_ppvar[2]._pval = &prop_ion->param[4]; /* _ion_dinadv */
 
}
 static void _initlists();
 static void _update_ion_pointer(Datum*);
 extern Symbol* hoc_lookup(const char*);
extern void _nrn_thread_reg(int, int, void(*f)(Datum*));
extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
extern void _cvode_abstol( Symbol**, double*, int);

 void _naz_nature_reg() {
	int _vectorized = 0;
  _initlists();
 	ion_reg("na", -10000.);
 	_na_sym = hoc_lookup("na_ion");
 	register_mech(_mechanism, nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init, hoc_nrnpointerindex, 0);
 _mechtype = nrn_get_mechtype(_mechanism[1]);
     _nrn_setdata_reg(_mechtype, _setdata);
     _nrn_thread_reg(_mechtype, 2, _update_ion_pointer);
  hoc_register_dparam_size(_mechtype, 3);
 	hoc_register_cvode(_mechtype, _ode_count, 0, 0, 0);
 	hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
 	ivoc_help("help ?1 na /Users/cweaver/research/Neuron/Coskren/MorphologyPaperTwo/Scripts/NeuronMechanisms/x86_64/naz_nature.mod\n");
 hoc_register_limits(_mechtype, _hoc_parm_limits);
 hoc_register_units(_mechtype, _hoc_parm_units);
 }
 static double _zmexp , _zhexp ;
 static double *_t_minf;
 static double *_t__zmexp;
 static double *_t_hinf;
 static double *_t__zhexp;
static int _reset;
static char *modelname = "";

static int error;
static int _ninits = 0;
static int _match_recurse=1;
static void _modl_cleanup(){ _match_recurse=1;}
static int _f_trates(double);
static int rates(double);
static int states();
static int trates(double);
 static void _n_trates(double);
 
static int  states (  ) {
   trates ( _threadargscomma_ v + vshift ) ;
   m = m + _zmexp * ( minf - m ) ;
   h = h + _zhexp * ( hinf - h ) ;
   
/*VERBATIM*/
        return 0;
  return 0; }
 
static void _hoc_states(void) {
  double _r;
   _r = 1.;
 states (  );
 hoc_retpushx(_r);
}
 static double _mfac_trates, _tmin_trates;
 static void _check_trates();
 static void _check_trates() {
  static int _maktable=1; int _i, _j, _ix = 0;
  double _xi, _tmax;
  static double _sav_dt;
  static double _sav_celsius;
  static double _sav_temp;
  static double _sav_Ra;
  static double _sav_Rb;
  static double _sav_Rd;
  static double _sav_Rg;
  static double _sav_tha;
  static double _sav_thi1;
  static double _sav_thi2;
  static double _sav_qa;
  static double _sav_qi;
  static double _sav_qinf;
  if (!usetable) {return;}
  if (_sav_dt != dt) { _maktable = 1;}
  if (_sav_celsius != celsius) { _maktable = 1;}
  if (_sav_temp != temp) { _maktable = 1;}
  if (_sav_Ra != Ra) { _maktable = 1;}
  if (_sav_Rb != Rb) { _maktable = 1;}
  if (_sav_Rd != Rd) { _maktable = 1;}
  if (_sav_Rg != Rg) { _maktable = 1;}
  if (_sav_tha != tha) { _maktable = 1;}
  if (_sav_thi1 != thi1) { _maktable = 1;}
  if (_sav_thi2 != thi2) { _maktable = 1;}
  if (_sav_qa != qa) { _maktable = 1;}
  if (_sav_qi != qi) { _maktable = 1;}
  if (_sav_qinf != qinf) { _maktable = 1;}
  if (_maktable) { double _x, _dx; _maktable=0;
   _tmin_trates =  vmin ;
   _tmax =  vmax ;
   _dx = (_tmax - _tmin_trates)/199.; _mfac_trates = 1./_dx;
   for (_i=0, _x=_tmin_trates; _i < 200; _x += _dx, _i++) {
    _f_trates(_x);
    _t_minf[_i] = minf;
    _t__zmexp[_i] = _zmexp;
    _t_hinf[_i] = hinf;
    _t__zhexp[_i] = _zhexp;
   }
   _sav_dt = dt;
   _sav_celsius = celsius;
   _sav_temp = temp;
   _sav_Ra = Ra;
   _sav_Rb = Rb;
   _sav_Rd = Rd;
   _sav_Rg = Rg;
   _sav_tha = tha;
   _sav_thi1 = thi1;
   _sav_thi2 = thi2;
   _sav_qa = qa;
   _sav_qi = qi;
   _sav_qinf = qinf;
  }
 }

 static int trates(double _lv){ _check_trates();
 _n_trates(_lv);
 return 0;
 }

 static void _n_trates(double _lv){ int _i, _j;
 double _xi, _theta;
 if (!usetable) {
 _f_trates(_lv); return; 
}
 _xi = _mfac_trates * (_lv - _tmin_trates);
 _i = (int) _xi;
 if (_xi <= 0.) {
 minf = _t_minf[0];
 _zmexp = _t__zmexp[0];
 hinf = _t_hinf[0];
 _zhexp = _t__zhexp[0];
 return; }
 if (_i >= 199) {
 minf = _t_minf[199];
 _zmexp = _t__zmexp[199];
 hinf = _t_hinf[199];
 _zhexp = _t__zhexp[199];
 return; }
 _theta = _xi - (double)_i;
 minf = _t_minf[_i] + _theta*(_t_minf[_i+1] - _t_minf[_i]);
 _zmexp = _t__zmexp[_i] + _theta*(_t__zmexp[_i+1] - _t__zmexp[_i]);
 hinf = _t_hinf[_i] + _theta*(_t_hinf[_i+1] - _t_hinf[_i]);
 _zhexp = _t__zhexp[_i] + _theta*(_t__zhexp[_i+1] - _t__zhexp[_i]);
 }

 
static int  _f_trates (  double _lv ) {
   double _ltinc ;
 rates ( _threadargscomma_ _lv ) ;
   tadj = pow( q10 , ( ( celsius - temp ) / 10.0 ) ) ;
   _ltinc = - dt * tadj ;
   _zmexp = 1.0 - myexp ( _threadargscomma_ _ltinc / mtau ) ;
   _zhexp = 1.0 - myexp ( _threadargscomma_ _ltinc / htau ) ;
    return 0; }
 
static void _hoc_trates(void) {
  double _r;
    _r = 1.;
 trates (  *getarg(1) );
 hoc_retpushx(_r);
}
 
static int  rates (  double _lvm ) {
   double _la , _lb ;
 _la = trap0 ( _threadargscomma_ _lvm , tha , Ra , qa ) ;
   _lb = trap0 ( _threadargscomma_ - _lvm , - tha , Rb , qa ) ;
   mtau = 1.0 / ( _la + _lb ) ;
   minf = _la * mtau ;
   _la = trap0 ( _threadargscomma_ _lvm , thi1 , Rd , qi ) ;
   _lb = trap0 ( _threadargscomma_ - _lvm , - thi2 , Rg , qi ) ;
   htau = 1.0 / ( _la + _lb ) ;
   hinf = 1.0 / ( 1.0 + myexp ( _threadargscomma_ ( _lvm - thinf ) / qinf ) ) ;
    return 0; }
 
static void _hoc_rates(void) {
  double _r;
   _r = 1.;
 rates (  *getarg(1) );
 hoc_retpushx(_r);
}
 
double myexp (  double _lx ) {
   double _lmyexp;
 if ( _lx < - 100.0 ) {
     _lmyexp = 0.0 ;
     }
   else {
     _lmyexp = exp ( _lx ) ;
     }
   
return _lmyexp;
 }
 
static void _hoc_myexp(void) {
  double _r;
   _r =  myexp (  *getarg(1) );
 hoc_retpushx(_r);
}
 
double trap0 (  double _lv , double _lth , double _la , double _lq ) {
   double _ltrap0;
 if ( fabs ( _lv / _lth ) > 1e-6 ) {
     _ltrap0 = _la * ( _lv - _lth ) / ( 1.0 - myexp ( _threadargscomma_ - ( _lv - _lth ) / _lq ) ) ;
     }
   else {
     _ltrap0 = _la * _lq ;
     }
   
return _ltrap0;
 }
 
static void _hoc_trap0(void) {
  double _r;
   _r =  trap0 (  *getarg(1) , *getarg(2) , *getarg(3) , *getarg(4) );
 hoc_retpushx(_r);
}
 
static int _ode_count(int _type){ hoc_execerror("na", "cannot be used with CVODE"); return 0;}
 extern void nrn_update_ion_pointer(Symbol*, Datum*, int, int);
 static void _update_ion_pointer(Datum* _ppvar) {
   nrn_update_ion_pointer(_na_sym, _ppvar, 0, 0);
   nrn_update_ion_pointer(_na_sym, _ppvar, 1, 3);
   nrn_update_ion_pointer(_na_sym, _ppvar, 2, 4);
 }

static void initmodel() {
  int _i; double _save;_ninits++;
 _save = t;
 t = 0.0;
{
  h = h0;
  m = m0;
 {
   trates ( _threadargscomma_ v + vshift ) ;
   m = minf ;
   h = hinf ;
   }
  _sav_indep = t; t = _save;

}
}

static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v = _v;
  ena = _ion_ena;
 initmodel();
 }}

static double _nrn_current(double _v){double _current=0.;v=_v;{ {
   gna = tadj * gbar * m * m * m * h ;
   ina = ( 1e-4 ) * gna * ( v - ena ) ;
   }
 _current += ina;

} return _current;
}

static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
  ena = _ion_ena;
 _g = _nrn_current(_v + .001);
 	{ double _dina;
  _dina = ina;
 _rhs = _nrn_current(_v);
  _ion_dinadv += (_dina - ina)/.001 ;
 	}
 _g = (_g - _rhs)/.001;
  _ion_ina += ina ;
#if CACHEVEC
  if (use_cachevec) {
	VEC_RHS(_ni[_iml]) -= _rhs;
  }else
#endif
  {
	NODERHS(_nd) -= _rhs;
  }
 
}}

static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type){
Node *_nd; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml];
#if CACHEVEC
  if (use_cachevec) {
	VEC_D(_ni[_iml]) += _g;
  }else
#endif
  {
     _nd = _ml->_nodelist[_iml];
	NODED(_nd) += _g;
  }
 
}}

static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type){
 double _break, _save;
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
 _nd = _ml->_nodelist[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 _break = t + .5*dt; _save = t;
 v=_v;
{
  ena = _ion_ena;
 { {
 for (; t < _break; t += dt) {
 error =  states();
 if(error){fprintf(stderr,"at line 90 in file naz_nature.mod:\n        SOLVE states\n"); nrn_complain(_p); abort_run(error);}
 
}}
 t = _save;
 } }}

}

static void terminal(){}

static void _initlists() {
 int _i; static int _first = 1;
  if (!_first) return;
   _t_minf = makevector(200*sizeof(double));
   _t__zmexp = makevector(200*sizeof(double));
   _t_hinf = makevector(200*sizeof(double));
   _t__zhexp = makevector(200*sizeof(double));
_first = 0;
}
