: Documentation: https://github.com/fietkiewicz/PointerBuilder
: Description: Closed-loop model of neural control for respiration.
NEURON {
SUFFIX na
POINTER nPointer
RANGE C ,Ek,El,Ena,Esyn,gk,gl,gna,gnap ,h_inf ,Ik ,Il ,Ina ,Inap ,Itonic ,m_inf ,mp_inf ,n_inf ,sigma_h ,sigma_m ,sigma_mp ,sigma_n ,tau_h ,tau_n ,taulb ,taumax_h ,taumax_n ,theta_h ,theta_m ,theta_mp ,theta_n
USEION na WRITE ina
}
PARAMETER {
: maximal conductances
gnap=2.8 gna=28 gk=11.2 gl=2.8
: reversal potentials
Ena=50 Ek=-85 El=-65 Esyn=0
: persistent sodium
theta_mp = -40 sigma_mp = -6
theta_h = -48 sigma_h = 6 taumax_h = 10000
: transient sodium
theta_m = -34 sigma_m = -5
: potassium
theta_n = -29 sigma_n = -4 taumax_n = 10
}
ASSIGNED {nPointer i gtonic h_inf ik ina Il Ina Inap Itonic m_inf mp_inf n_inf tau_h tau_n taulb v}
BREAKPOINT {
: transient sodium
m_inf = 1/(1+exp((v-theta_m)/sigma_m))
ina = gna*pow(m_inf,3)*(1-nPointer)*(v-Ena)
}