celsius=14
load_file("nparams.hoc")
load_file("custominit.hoc")
load_file("cell_d.hoc")
mono_syn_delay = 2.6 //ms 3.5
syn_latency = 1.8 //ms
ni = vt_CS.size() // GET NUMBER OF TONIC CELLS
cell_nr = cell_nr-1
objref p_synE, t_synE[ni]
objectvar phasiccell
rho=vp_rho.x(cell_nr)
Le=vp_Le.x(cell_nr)
CS=vp_CS.x(cell_nr)
GS=vp_GS.x(cell_nr)
GSh=vp_GSh.x(cell_nr)
GNa=p_GNa
GK=p_GK
GKCa=p_GKCa
tn=p_tn
tca=p_tca
N=p_N
GKd=vp_GKd.x(cell_nr)
tfac=p_tfac
El=p_El
Els=p_Els
bn=p_bn
gn=p_gn
phasiccell = new cell(N, rho, Le, CS, GS, GSh, GNa, GK, GKd, tfac, GKCa, El, Els, bn, gn, tn, tca)
phasiccell.soma p_synE = new Exp2Syn(0.5)
p_synE.tau1 = p_tau1E
p_synE.tau2 = p_tau2E
p_synE.e = 0
objectvar toniccell[ni]
for i = 0, ni-1 {
t_rho=vt_rho.x(i)
t_Le=vt_Le.x(i)
t_CS=vt_CS.x(i)
t_GS=vt_GS.x(i)
t_GSh=vt_GSh.x(i)
t_GNa=vt_GNa.x(i)
t_GK=vt_GK.x(i)
t_GKCa=vt_GKCa.x(i)
t_tn=vt_tn.x(i)
t_tca=vt_tca.x(i)
toniccell[i] = new cell(t_N, t_rho, t_Le, t_CS, t_GS, t_GSh, t_GNa, t_GK, t_GKd, t_tfac, t_GKCa, t_El, t_Els, t_bn, t_gn, t_tn, t_tca)
toniccell[i].soma t_synE[i] = new Exp2Syn(0.5)
t_synE[i].tau1 = t_tau1E
t_synE[i].tau2 = t_tau2E
t_synE[i].e = 0
}
objref ncI[ni], synI[ni]
if (ton_inhib == 1){
for i = 0,ni-1 {
phasiccell.soma synI[i] = new Exp2Syn(0.5)
synI[i].tau1 = tau1In
synI[i].tau2 = tau2In
synI[i].e = EIn
toniccell[i].soma ncI[i] = new NetCon(&v(0.5), synI[i], -30, syn_latency, GIn) //weight in uS
}
}
objref synfile, syntimes, interspiket, p_ncE, t_ncE[ni], nil, fih
synfile = new File()
synfile.ropen("syntimes570.txt")
tstop = 5000
syntimes = new Vector()
syntimes.scanf(synfile)
p_ncE = new NetCon(nil, p_synE, 0.5, 0, p_GE)
for i = 0,ni-1 {
t_ncE[i] = new NetCon(nil, t_synE[i], 0.5, 0, t_GE)
}
fih = new FInitializeHandler("loadqueue()")
proc loadqueue() { local ii
for ii=0,syntimes.size()-1 p_ncE.event(syntimes.x[ii]+mono_syn_delay)
for i = 0,ni-1 {
for ii=0,syntimes.size()-1 t_ncE[i].event(syntimes.x[ii]+mono_syn_delay)
}
}
access phasiccell.soma
objectvar window, window2
window = new Graph(0)
window.size(0,5000,-80,40)
window.view(0, -80, 5000, 120, 325, 127, 699.84, 250.24)
graphList[0].append(window)
window.addexpr("phasiccell.soma.v(.5)", 1, 1, 0.8, 0.9, 2)
window2 = new Graph(0)
window2.size(0,5000,-80,40)
window2.view(0, -80, 5000, 120, 324, 452, 699.84, 250.24)
graphList[0].append(window2)
window2.addexpr("toniccell[3].soma.v(.5)", 1, 1, 0.8, 0.9, 2)
run()