TITLE tonic GABA current according to Pavlov et al., 2009 in J Neurosci
NEURON{
SUFFIX tonic
NONSPECIFIC_CURRENT itonic
RANGE itonic, e, gtonic, minf
}
UNITS {
(nA) = (nanoamp)
(mV) = (millivolt)
(uS) = (microsiemens)
}
PARAMETER {
gtonic=0.001 (siemens/cm2) <0, 1e9>
e = -70 (mV)
}
ASSIGNED{
v (mV)
itonic (milliamp/cm2)
minf
}
BREAKPOINT {
minf=a(v)/(a(v)+b(v))
itonic=gtonic*minf*(v-e)
}
FUNCTION a(v(mV)) {
LOCAL x
if (fabs(v+20) > 1e-5) {
x = 0.1 * (v + 20)
}else{
x = 0.1
}
a = (50 * x / (1 - exp(-x)))
}
FUNCTION b(v(mV)) {
LOCAL x
if (fabs(v-10) > 1e-5) {
x = -0.08 * (v - 10)
} else {
x = -0.08
}
b = (20 * x / (1 - exp(-x)))
}