/*-------------------------------------------------------------- TEMPLATE FILE FOR FAST-SPIKING CORTICAL INTERNEURON --------------------------------------------------- One compartment model and currents derived from: Pospischil, M., Toledo-Rodriguez, M., Monier, C., Piwkowska, Z., Bal, T., Fregnac, Y., Markram, H. and Destexhe, A. Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons. Biological Cybernetics 99: 427-441, 2008. - one compartment model - passive - HH: Traub Alain Destexhe, CNRS, 2008 --------------------------------------------------------------*/ print " " print " << defining template for one-compartment sIN cell >> " print " " begintemplate sIN // create a new template object public soma create soma[1] proc init() { local v_potassium, v_sodium v_potassium = -100 // potassium reversal potential v_sodium = 50 // sodium reversal potential soma { Ra = 100 // geometry nseg = 1 diam = 67 L = 67 // so that area is about 14000 um2 cm = 1 insert pas // leak current e_pas = -70 // g_pas = 5e-5 g_pas = 0.00015 // Rin = 48Meg // conversion with McC units: // g(S/cm2) = g(nS)*1e-9/29000e-8 // = g(nS) * 3.45e-6 insert hh2 // Hodgin-Huxley INa and IK ek = v_potassium ena = v_sodium vtraub_hh2 = -55 // resting Vm, BJ was -55 gnabar_hh2 = 0.05 // McCormick=15 muS, thal was 0.09 // gkbar_hh2 = 0.007 // McCormick=2 muS, thal was 0.01 // gkbar_hh2 = 0.004 gkbar_hh2 = 0.01 // spike duration of interneurons } print " " print "<< sIN: passive, INa, IK inserted >>" print " " } endtemplate sIN