TITLE Sodium persistent current for RD Traub, J Neurophysiol 89:909-921, 2003
COMMENT
Implemented by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu)
ENDCOMMENT
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
}
NEURON {
SUFFIX nap
USEION na READ ena WRITE ina
RANGE gbar, ina, minf, mtau, gna :, vshift
}
PARAMETER {
gbar = 1e-4 (mho/cm2)
vshift = 0
v ena (mV)
}
ASSIGNED {
ina (mA/cm2)
minf (1)
mtau (ms)
gna (mho/cm2)
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
gna = gbar * m
ina = gna * ( v - ena )
}
INITIAL {
settables(v-vshift)
m = minf
:m = 0
}
DERIVATIVE states {
settables(v-vshift)
m' = ( minf - m ) / mtau
}
UNITSOFF
PROCEDURE settables(v) {
TABLE minf, mtau FROM -120 TO 40 WITH 641
: minf = 1 / ( 1 + exp( ( - v - 48 ) / 10 ) )
minf = 1 / ( 1 + exp( ( - v - 48 ) / 5 ) )
if( v < -40.0 ) {
mtau = 100*(0.025 + 0.14 * exp( ( v + 40 ) / 10 ))
}else{
mtau = 100*(0.02 + 0.145 * exp( ( - v - 40 ) / 10 ))
}
}
UNITSON