create axon, Can, Stick
ignored_diam = 0.3 // note these diameters are overwritten by alz_axon.hoc
axon { nseg=19 L=565.723 Ra=50
/*location 0 attached to cell 0*/
/* First segment only */
insert capacitance { cm=1}
insert morphology { diam=ignored_diam } // 0.397111}
insert nax { sh_nax=0 gbar_nax=0.125}
insert na_ion { ena=50}
insert kdr { gkdrbar_kdr=0.01}
insert k_ion { ek=-77}
}
// store original conductance density values for later modifications
axon {
gbar_nax_orig = gbar_nax
gkdrbar_kdr_orig = gkdrbar_kdr
}
Can { nseg=1 L=5 Ra=50
Stick connect Can (0), 1
/* First segment only */
insert morphology { diam=ignored_diam } // 5
insert capacitance { cm=1}
// assume passive (g's=0 below as default)
insert nax { sh_nax=0 gbar_nax=0}
insert na_ion { ena=50}
insert kdr { gkdrbar_kdr=0}
insert k_ion { ek=-77}
}
Stick { nseg=1 L=5 Ra=50
axon connect Stick (0), 0.5
/* First segment only */
insert morphology { diam=ignored_diam} //0.3
insert capacitance { cm=1}
// assume passive (g's=0 below as default)
insert nax { sh_nax=0 gbar_nax=0}
insert na_ion { ena=50}
insert kdr { gkdrbar_kdr=0}
insert k_ion { ek=-77}
}
// places pas leak channel everywhere
forall {
insert pas { g_pas=3.16228e-05 e_pas=-70.525}
}
/*
create soma
soma {
L=1
diam=5
insert pas
e_pas = -70
} // a load to put on axon, increase soma size to mimick dend load
connect soma(1), axon(0)
*/