load_file("nrngui.hoc")
load_file("CellInit.hoc")
load_file("CellUpdate.hoc")
load_file("MechanismSwitch.hoc")
load_file("MainUi.hoc")
load_file("GeometricalParameters.hoc")
load_file("Simulations/SimFrapInCircleGeometry.hoc")
load_file("Simulations/SimFrapLine.hoc")
load_file("Simulations/SimSpatialVoltageDistributions.hoc")
load_file("Simulations/SimConstantElectricalSimulations.hoc")
load_file("Simulations/SimFrequencyElectricalSimulation.hoc")
load_file("Simulations/SimCalciumDynamics.hoc")
load_file("Simulations/SimCalciumWave.hoc")
load_file("Simulations/SimGlutamate.hoc")
load_file("Simulations/SimPotassium.hoc")
// Sets initial params.
proc initParamsMain() {
GapResistance = 100000 // Megaohm
potential = -85 // mV
res_gap(GapResistance, potential)
Z_coordinate = 10 // the stochastic parameter changes the Z-distribution of astrocytes branches
ScalingDiam = 0.127 // the parameter scales the diameter of the central dendrites
LengthXY = 5.5
LengthZ =2
ShiftXY=200
Distance=2
jd = 0
SwitchOffGapJunction=1
if (ScaleGeometryParameters==1) {
stretch(Z_coordinate, ScalingDiam)
} else {
// stretchXY( LengthXY, LengthZ, ShiftXY)
}
//
// This parameter defines how fast calcium relaxes between neighboring astrocytes.
// The larger value means a slower connection between astrocytes.
//***************************************************************************************
insertGapJunc()
CaGapFlux(jd, SwitchOffGapJunction)
//***************************************************************************************
InsertElectricMechanisms(1)
DensityGluTransporters = 1e12 // 1/um2
MaxDimLeaves = 2.5 // um
MinDimLeaves = 0.1 // um
MaxLenLeaves = 0.12 // um
MinLenLeaves = 0.1 // um
GPassive = 0.001 // Ohm cm
setLeaves(MaxDimLeaves, MinDimLeaves, MaxLenLeaves, MinLenLeaves, nanoDistrLoaded, DensityGluTransporters, GPassive)
MaxDimStalk = 0.1 // um
MinDimStalk = 0.1 // um
MaxLenStalk = 1*12/NumberLeaves // um
MinLenStalk = 0.9*12/NumberLeaves // um
setStalks(MaxDimStalk, MinDimStalk, MaxLenStalk, MinLenStalk, nanoDistrLoaded, DensityGluTransporters)
OnlySingleGluSimulations = 1 // parameter for Glu and Potassium single voltage clamp mechanism
dt = 1
steps_per_ms = 1 // ms
tstop = 10000 // ms
v_init = -85 // mV
finitialize(v_init)
}
// Opens the main program window.
proc runMain() {
initCell()
initParamsMain()
showRunPanel()
showMainUi()
}