TITLE Potassium Current
COMMENT
Author: Ronald van Elburg
Taken from model for fast spiking neuron in J. Tegner, A. Compte,
X.J. Wang, J. Neurosci. 22(20): 9053-9062, 2002
Modifications:
ID Date Authors Email Description
M_001
ENDCOMMENT
UNITS {
: (Abbreviation)= (Unit)
(mV) = (millivolt)
(mA) = (milliamp)
(pS) = (picosiemens)
(um) = (micron)
: Abbreviation = (Constant) (Unit)
}
NEURON {
SUFFIX KPyr
USEION k READ ek WRITE ik
RANGE gbar, ik
GLOBAL v_table_min, v_table_max,phin
}
PARAMETER {
: Parameter =Initial Value (Units) Description
gbar = 1 (pS/um2)
v (mV)
ek (mV)
phin = 1 (1)
: Table settings
v_table_min = -120 (mV)
v_table_max = 100 (mV)
}
ASSIGNED {
: Parameter Units Description
ik (mA/cm2)
nalpha (1/ms)
nbeta (1/ms)
}
STATE {
n (1)
}
BREAKPOINT {
settables(v)
SOLVE states METHOD cnexp
ik =(1e-4)*gbar * n * n * n * n * (v - ek)
}
INITIAL {
settables(v)
n=nalpha/(nalpha+nbeta)
}
DERIVATIVE states {
settables(v)
n' =phin* ( nalpha*(1-n) -nbeta*n)
}
UNITSOFF
PROCEDURE settables(v (mV)) {
TABLE nalpha, nbeta FROM v_table_min TO v_table_max WITH 961
nalpha = 0.032*vtrap(-(v+52),0.2)
nbeta = 0.5*exp(-0.025*(57+v))
}
UNITSON
FUNCTION vtrap(x, k) {
if (fabs(x) < 1e-6) {
vtrap = 1/(k * exp(k*x))
} else {
vtrap = x / (exp(k*x) - 1)
}
}