TITLE jsr.mod VCN conductances
COMMENT
Ih for VCN neurons - average from several studies in auditory neurons
Implementation by Paul B. Manis, April (JHU) and Sept, (UNC)1999.
revised 2/28/04 pbm
pmanis@med.unc.edu
ENDCOMMENT
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(nA) = (nanoamp)
}
NEURON {
SUFFIX ih
NONSPECIFIC_CURRENT i
RANGE ghbar, gh, ih
GLOBAL rinf, rtau
RANGE eh
}
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
PARAMETER {
v (mV)
celsius = 22 (degC)
dt (ms)
ghbar = 0.00318 (mho/cm2) <0,1e9>
eh = -43 (mV)
}
STATE {
r
}
ASSIGNED {
gh (mho/cm2)
i (mA/cm2)
rinf
rtau (ms)
}
LOCAL rexp
BREAKPOINT {
SOLVE states
gh = ghbar*r
i = gh*(v - eh)
}
UNITSOFF
INITIAL {
trates(v)
r = rinf
}
PROCEDURE states() { :Computes state variables m, h, and n
trates(v) : at the current v and dt.
r = r + rexp*(rinf-r)
VERBATIM
return 0;
ENDVERBATIM
}
LOCAL q10
PROCEDURE rates(v) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
q10 = 3^((celsius - 22)/10)
rinf = 1 / (1+exp((v + 76) / 7))
rtau = (100000 / (237*exp((v+60) / 12) + 17*exp(-(v+60) / 14))) + 25
}
PROCEDURE trates(v) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
LOCAL tinc
TABLE rinf, rexp
DEPEND dt, celsius FROM -200 TO 150 WITH 350
rates(v) : not consistently executed from here if usetable_hh == 1
: so don't expect the tau values to be tracking along with
: the inf values in hoc
tinc = -dt * q10
rexp = 1 - exp(tinc/rtau)
}
FUNCTION vtrap(x,y) { :Traps for 0 in denominator of rate eqns.
if (fabs(x/y) < 1e-6) {
vtrap = y*(1 - x/y/2)
}else{
vtrap = x/(exp(x/y) - 1)
}
}
UNITSON