TITLE transient potassium (A-) current
COMMENT Equations from
Huguenard JR, McCormick DA (1992) Simulation of the currents involved
in rhythmic oscillations in thalamic relay neurons. J Neurophys 68(4):
1373-1383.
>< Temperature adjusts time constants measured at 23.5 degC.
>< Written by Arthur Houweling for MyFirstNEURON.
ENDCOMMENT
NEURON {
SUFFIX iA
USEION k READ ek WRITE ik
RANGE gk, minf, mtau, hinf, htau, ik
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
v (mV)
celsius (degC)
ek (mV)
gk= 3.45e-3 (mho/cm2)
}
STATE { m h }
ASSIGNED {
ik (mA/cm2)
mtau (ms)
htau (ms)
minf
hinf
tadj
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik= gk* m^4* h* (v- ek)
}
DERIVATIVE states {
rates()
m'= (minf- m)/ mtau
h'= (hinf- h)/ htau
}
INITIAL { UNITSOFF
tadj= 3^ ((celsius- 23.5)/ 10)
rates()
m= minf
h= hinf
}
PROCEDURE rates() {
minf= 1/ (1+exp(-(v+60)/8.5))
hinf= 1/ (1+ exp((v+ 78)/ 6))
mtau= (1/ (exp((v+ 35.82)/ 19.69)+ exp(-(v+ 79.69)/ 12.7))+ 0.37)/ tadj
if (v< -63) { htau= 1/ (( exp((v+ 46.05)/ 5)+ exp(-(v+ 238.4)/ 37.45)))/ tadj }
else { htau= 19/ tadj }
}