TITLE K_No.mod nodal slow potassium channel
COMMENT
This is the original Hodgkin-Huxley treatment for the set of potassium channel found
in the squid giant axon membrane.
Some parameters have been changed to correspond to McIntyre and Grill (2002) "Extracellular
stimulation of central neurons"
Author: Balbi
ENDCOMMENT
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(S) = (siemens)
}
NEURON {
SUFFIX K_No
USEION k READ ek WRITE ik
RANGE gkmax, gk
RANGE sinf, stau
}
PARAMETER {
gkmax = 0.08 (S/cm2) <0,1e9>
}
STATE {
s
}
ASSIGNED {
v (mV)
ek (mV)
gk (S/cm2)
ik (mA/cm2)
sinf
stau (ms)
}
BREAKPOINT {
SOLVE states METHOD cnexp
gk = gkmax*s
ik = gk*(v - ek)
}
INITIAL {
rates(v)
s = sinf
}
DERIVATIVE states {
rates(v)
s' = (sinf-s)/stau
}
PROCEDURE rates(v(mV)) {
:Call once from HOC to initialize inf at resting v.
LOCAL alpha, beta, sum
UNITSOFF
:"s" potassium activation system
alpha = 0.3/(1+exp((v+43)/-5))
beta = 0.03/(1+exp((v+80)/-1))
sum = alpha + beta
stau = 1/sum
sinf = alpha/sum
}
UNITSON