// B5FScell3Dpk.p // Format of file : // x,y,z,dia are in microns, all other units are SI (Meter Kilogram Sec Amp) // In polar mode 'r' is in microns, theta and phi in degrees // Control line options start with a '*' // The format for each compartment parameter line is : //name parent r theta phi d ch dens ... //in polar mode, and in cartesian mode : //name parent x y z d ch dens ... // For channels, "dens" = maximum conductance per unit area of compartment // For spike elements, "dens" is the spike threshold // Coordinate mode *relative *cartesian *asymmetric // Specifying constants *set_compt_param RM 2.50 //0.33333 (2.50) *set_compt_param RA 2.00 //0.3 (2.00) *set_compt_param CM 0.01 //0.01 (0.01) *set_compt_param EREST_ACT -0.07 // *set_compt_param ELEAK -0.0666 // -0.0735 //SOMA ************************************************************* // For the soma, use the leakage potential (-0.07 + 0.0106) for Em //*set_compt_param ELEAK -0.0594 // Actually, after Cunningham et al. PNAS 2004;101:7152-7157, will maintain // leakage potential at ELEAK -0.07 soma none 0 0 20 15.0 Ca_s10 -5.5173713E16 NaF10 900 \ KDR10 1000 KA10 1 CaH10 1 KCs10 1 // KCs10 250 KA10 10 //*set_compt_param ELEAK -0.075 *set_compt_param RM 2.50 //0.33333 (2.50) *set_compt_param RA 2.00 //0.3 (2.00) *set_compt_param CM 0.01 //0.01 (0.01) //PROXIMAL DENDRITE COMPARTMENTS *************************************** // proxdendN Cunningham et al., PNAS 2004;101:7152-7157 proxdendN soma 0 0 40 2.12 Ca_d10 -3.90380092E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // proxdendE Cunningham et al., PNAS 2004;101:7152-7157 proxdendE soma 40 0 0 2.12 Ca_d10 -3.90380092E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // proxdendS Cunningham et al., PNAS 2004;101:7152-7157 proxdendS soma 0 0 -40 2.12 Ca_d10 -3.90380092E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // proxdendW Cunningham et al., PNAS 2004;101:7152-7157 proxdendW soma -40 0 0 2.12 Ca_d10 -3.90380092E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 *set_compt_param RM 2.50 //0.33333 (2.50) *set_compt_param RA 2.00 //0.3 (2.00) *set_compt_param CM 0.01 //0.01 (0.01) //*set_compt_param ELEAK -0.075 //North DISTAL DENDRITE COMPARTMENTS *************************************** // distdendNlonga Cunningham et al., PNAS 2004;101:7152-7157 distdendNlonga proxdendN -6.84 11.8 37.6 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendNlongb Cunningham et al., PNAS 2004;101:7152-7157 distdendNlongb distdendNlonga -6.84 11.8 37.6 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNlongc Cunningham et al., PNAS 2004;101:7152-7157 distdendNlongc distdendNlongb -6.84 11.8 37.6 0.84 Ca_d10 -9.876647E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNlongd Cunningham et al., PNAS 2004;101:7152-7157 distdendNlongd distdendNlongc -6.84 11.8 37.6 0.84 Ca_d10 -9.8765206E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNlonge Cunningham et al., PNAS 2004;101:7152-7157 distdendNlonge distdendNlongd -6.84 11.8 37.6 0.84 Ca_d10 -9.8767418E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNlongf Cunningham et al., PNAS 2004;101:7152-7157 distdendNlongf distdendNlonge -6.84 11.8 37.6 0.84 Ca_d10 -9.876737E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNlongg Cunningham et al., PNAS 2004;101:7152-7157 distdendNlongg distdendNlongf -6.84 11.8 37.6 0.84 Ca_d10 -9.8760354E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNmida Cunningham et al., PNAS 2004;101:7152-7157 distdendNmida proxdendN 6.84 -11.8 37.6 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendNmidb Cunningham et al., PNAS 2004;101:7152-7157 distdendNmidb distdendNmida 6.84 -11.8 37.6 1.34 Ca_d10 -9.8765082E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNmidc Cunningham et al., PNAS 2004;101:7152-7157 distdendNmidc distdendNmidb 6.84 -11.8 37.6 1.34 Ca_d10 -6.2070847E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNshorta Cunningham et al., PNAS 2004;101:7152-7157 distdendNshorta distdendNlonga 6.84 -11.8 37.6 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendNshortb Cunningham et al., PNAS 2004;101:7152-7157 distdendNshortb distdendNshorta 6.84 -11.8 37.6 0.84 Ca_d10 -9.8768566E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 //East DISTAL DENDRITE COMPARTMENTS *************************************** // distdendElonga Cunningham et al., PNAS 2004;101:7152-7157 distdendElonga proxdendE 32.5 18.8 13.68 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendElongb Cunningham et al., PNAS 2004;101:7152-7157 distdendElongb distdendElonga 32.5 18.8 13.68 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendElongc Cunningham et al., PNAS 2004;101:7152-7157 distdendElongc distdendElongb 32.5 18.8 13.68 0.84 Ca_d10 -9.876647E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendElongd Cunningham et al., PNAS 2004;101:7152-7157 distdendElongd distdendElongc 32.5 18.8 13.68 0.84 Ca_d10 -9.8765206E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendElonge Cunningham et al., PNAS 2004;101:7152-7157 distdendElonge distdendElongd 32.5 18.8 13.68 0.84 Ca_d10 -9.8767418E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendElongf Cunningham et al., PNAS 2004;101:7152-7157 distdendElongf distdendElonge 32.5 18.8 13.68 0.84 Ca_d10 -9.876737E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendElongg Cunningham et al., PNAS 2004;101:7152-7157 distdendElongg distdendElongf 32.5 18.8 13.68 0.84 Ca_d10 -9.8760354E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendEmida Cunningham et al., PNAS 2004;101:7152-7157 distdendEmida proxdendE 32.5 18.8 -13.68 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendEmidb Cunningham et al., PNAS 2004;101:7152-7157 distdendEmidb distdendEmida 32.5 18.8 -13.68 0.84 Ca_d10 -9.8765082E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendEmidc Cunningham et al., PNAS 2004;101:7152-7157 distdendEmidc distdendEmidb 32.5 18.8 -13.68 0.84 Ca_d10 -6.2070847E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendEshorta Cunningham et al., PNAS 2004;101:7152-7157 distdendEshorta distdendElonga 32.5 18.8 -13.68 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendEshortb Cunningham et al., PNAS 2004;101:7152-7157 distdendEshortb distdendEshorta 32.5 18.8 -13.68 0.84 Ca_d10 -9.8768566E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 //South DISTAL DENDRITE COMPARTMENTS *************************************** // distdendSlonga Cunningham et al., PNAS 2004;101:7152-7157 distdendSlonga proxdendS 6.84 -11.8 -37.6 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendSlongb Cunningham et al., PNAS 2004;101:7152-7157 distdendSlongb distdendSlonga 6.84 -11.8 -37.6 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSlongc Cunningham et al., PNAS 2004;101:7152-7157 distdendSlongc distdendSlongb 6.84 -11.8 -37.6 0.84 Ca_d10 -9.876647E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSlongd Cunningham et al., PNAS 2004;101:7152-7157 distdendSlongd distdendSlongc 6.84 -11.8 -37.6 0.84 Ca_d10 -9.8765206E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSlonge Cunningham et al., PNAS 2004;101:7152-7157 distdendSlonge distdendSlongd 6.84 -11.8 -37.6 0.84 Ca_d10 -9.8767418E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSlongf Cunningham et al., PNAS 2004;101:7152-7157 distdendSlongf distdendSlonge 6.84 -11.8 -37.6 0.84 Ca_d10 -9.876737E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSlongg Cunningham et al., PNAS 2004;101:7152-7157 distdendSlongg distdendSlongf 6.84 -11.8 -37.6 0.84 Ca_d10 -9.8760354E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSmida Cunningham et al., PNAS 2004;101:7152-7157 distdendSmida proxdendS -6.84 11.8 -37.6 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendSmidb Cunningham et al., PNAS 2004;101:7152-7157 distdendSmidb distdendSmida -6.84 11.8 -37.6 0.84 Ca_d10 -9.8765082E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSmidc Cunningham et al., PNAS 2004;101:7152-7157 distdendSmidc distdendSmidb -6.84 11.8 -37.6 0.84 Ca_d10 -6.2070847E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSshorta Cunningham et al., PNAS 2004;101:7152-7157 distdendSshorta distdendSlonga -6.84 11.8 -37.6 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendSshortb Cunningham et al., PNAS 2004;101:7152-7157 distdendSshortb distdendSshorta -6.84 11.8 -37.6 0.84 Ca_d10 -9.8768566E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 //West DISTAL DENDRITE COMPARTMENTS *************************************** // distdendWlonga Cunningham et al., PNAS 2004;101:7152-7157 distdendWlonga proxdendW -32.5 -18.8 13.68 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendWlongb Cunningham et al., PNAS 2004;101:7152-7157 distdendWlongb distdendWlonga -32.5 -18.8 13.68 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWlongc Cunningham et al., PNAS 2004;101:7152-7157 distdendWlongc distdendWlongb -32.5 -18.8 13.68 0.84 Ca_d10 -9.876647E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWlongd Cunningham et al., PNAS 2004;101:7152-7157 distdendWlongd distdendWlongc -32.5 -18.8 13.68 0.84 Ca_d10 -9.8765206E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWlonge Cunningham et al., PNAS 2004;101:7152-7157 distdendWlonge distdendWlongd -32.5 -18.8 13.68 0.84 Ca_d10 -9.8767418E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWlongf Cunningham et al., PNAS 2004;101:7152-7157 distdendWlongf distdendWlonge -32.5 -18.8 13.68 0.84 Ca_d10 -9.876737E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWlongg Cunningham et al., PNAS 2004;101:7152-7157 distdendWlongg distdendWlongf -32.5 -18.8 13.68 0.84 Ca_d10 -9.8760354E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWmida Cunningham et al., PNAS 2004;101:7152-7157 distdendWmida proxdendW -32.5 -18.8 -13.68 1.34 Ca_d10 -6.2070579E17 NaF10 600 \ KDR10 1000 \ KA10 10 \ CaH10 1 KCd10 250 // distdendWmidb Cunningham et al., PNAS 2004;101:7152-7157 distdendWmidb distdendWmida -32.5 -18.8 -13.68 0.84 Ca_d10 -9.8765082E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWmidc Cunningham et al., PNAS 2004;101:7152-7157 distdendWmidc distdendWmidb -32.5 -18.8 -13.68 0.84 Ca_d10 -6.2070847E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWshorta Cunningham et al., PNAS 2004;101:7152-7157 distdendWshorta distdendWlonga -32.5 -18.8 -13.68 0.84 Ca_d10 -9.8766113E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // distdendWshortb Cunningham et al., PNAS 2004;101:7152-7157 distdendWshortb distdendWshorta -32.5 -18.8 -13.68 0.84 Ca_d10 -9.8768566E17 NaF10 100 \ KDR10 100 \ KA10 10 \ CaH10 2 KCd10 250 // Specifying constants for axonal compartment *set_compt_param RM 0.1 // (0.1) *set_compt_param RA 1.0 // (1.0) *set_compt_param CM 0.01 // (0.01) RC = 0.001 *set_compt_param ELEAK -0.0666 // axona Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axona soma 0 0 -25 1.4 NaF10 4000 \ KDR10 4000 \ KA10 10 // axonb Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axonb axona 0 0 -50 1.2 NaF10 4000 \ KDR10 4000 \ KA10 10 // axonLa Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axonLa axonb -8.7 0 -49.2 1.0 NaF10 4000 \ KDR10 4000 \ KA10 10 // axonLb Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axonLb axonLa -8.7 0 -49.2 1.0 NaF10 4000 \ KDR10 4000 \ KA10 10 // axonRa Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axonRa axonb 8.7 0 -49.2 1.0 NaF10 4000 \ KDR10 4000 \ KA10 10 // axonRb Fig 1. Traub et al., J Neurophysiol 2003;89:909-921 // Differs from Traub et al., in that axon is vertical axonRb axonRa 8.7 0 -49.2 1.0 NaF10 4000 \ KDR10 4000 \ KA10 10