// genesis // Setting the axonal propagation velocity float CABLE_VEL = 1 // scale factor = 1/(cable velocity) sec/meter float destlim = {TCR_nRT_destlim} /* * Usage : * volumeconnect source-path destination-path * [-relative] * [-sourcemask {box,ellipse} x1 y1 x2 y2] * [-sourcehole {box,ellipse} x1 y1 x2 y2] * [-destmask {box,ellipse} x1 y1 x2 y2] * [-desthole {box,ellipse} x1 y1 x2 y2] * [-probability p] */ echo Making connections from the TCR cells to the nRT cells. //TCR - nRT AMPA str s //Load synapse location array str locations = "proxdendN distdendNlonga distdendNmida proxdendE distdendElonga distdendEmida proxdendS distdendSlonga distdendSmida proxdendW distdendWlonga distdendWmida" foreach s ({arglist {locations}}) rvolumeconnect /TCRnet/TCR[]/soma/spk20 \ /nRTnet/nRT[]/{s}/Ex_ch21TCRAMPA@all \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -probability 0.042*{TCR_nRT_prob} end //TCR - nRT NMDA str s //Load synapse location array str locations = "proxdendN distdendNlonga distdendNmida proxdendE distdendElonga distdendEmida proxdendS distdendSlonga distdendSmida proxdendW distdendWlonga distdendWmida" foreach s ({arglist {locations}}) rvolumeconnect /TCRnet/TCR[]/soma/spk20 \ /nRTnet/nRT[]/{s}/Ex_ch21TCRNMDA@all \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -probability 0.042*{TCR_nRT_prob} end echo Setting weights and delays for TCR->nRT connections. // assigning delays using the volumedelay function /* * Usage : * volumedelay path * [-fixed delay] * [-radial propagation_velocity] * [-uniform range] (not used here) * [-gaussian sd max] (not used here) * [-exp mid max] (not used here) * [-absoluterandom] (not used here) */ rvolumedelay /TCRnet/TCR[]/soma/spk20 -radial {TCR_nRT_axdelayCV} -add -gaussian {TCR_nRT_axdelaystdev} {TCR_nRT_axdelaymaxdev} // TCR - nRT AMPA str s //Load synapse location array str locations = "distdendNlongb distdendNlongc distdendNmidb distdendNmidc distdendNshorta distdendNshortb distdendElongb distdendElongc distdendEmidb distdendEmidc distdendEshorta distdendEshortb distdendSlongb distdendSlongc distdendSmidb distdendSmidc distdendSshorta distdendSshortb distdendWlongb distdendWlongc distdendWmidb distdendWmidc distdendWshorta distdendWshortb" foreach s ({arglist {locations}}) syndelay /nRTnet/nRT[]/{s}/Ex_ch21TCRAMPA {TCR_nRT_syndelay} -add -gaussian {TCR_nRT_syndelaystdev} {TCR_nRT_syndelaymaxdev} end // TCR - nRT NMDA str s //Load synapse location array str locations = "distdendNlongb distdendNlongc distdendNmidb distdendNmidc distdendNshorta distdendNshortb distdendElongb distdendElongc distdendEmidb distdendEmidc distdendEshorta distdendEshortb distdendSlongb distdendSlongc distdendSmidb distdendSmidc distdendSshorta distdendSshortb distdendWlongb distdendWlongc distdendWmidb distdendWmidc distdendWshorta distdendWshortb" foreach s ({arglist {locations}}) syndelay /nRTnet/nRT[]/{s}/Ex_ch21TCRNMDA {TCR_nRT_syndelay} -add -gaussian {TCR_nRT_syndelaystdev} {TCR_nRT_syndelaymaxdev} end // assigning weights using the volumeweight function /* * Usage : * volumeweight sourcepath * [-fixed weight] * [-decay decay_rate max_weight min_weight] * [-uniform range] * [-gaussian sd max] * [-exponential mid max] * [-absoluterandom] */ rvolumeweight /TCRnet/TCR[]/soma/spk20 -decay {TCRdecayrate} {TCRmaxwgt} {TCRminwgt}