// ***** Insert mechanisms *****
for CELLINDEX = 0,cellList.count-1 {
hasGCL = 0
forsec cellList.o(CELLINDEX).allreg {
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
insert k_ion
ek = -93
insert na_ion
ena = 87.76
insert ca_ion
cao0_ca_ion = 2
cai0_ca_ion = 4.8e-05
if (issection(".*GCL.*")) {
hasGCL = 1
}
}
if (hasGCL) {
forsec cellList.o(CELLINDEX).regGCL {
insert pas
cm = 0.9
Ra = 200
g_pas = 1.38462e-05
e_pas = -70
insert Kir21
gkbar_Kir21 = 3.82215e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert Kv42
gkbar_Kv42 = 0.0010875
a0_Kv42 = 0.416
za_Kv42 = 1.1
b0_Kv42 = 0.0486
zb_Kv42 = -1.556
kco0_Kv42 = 0.347
zco_Kv42 = 0
koc0_Kv42 = 1.67
zoc_Kv42 = 0
kci_Kv42 = 0.04873
kic_Kv42 = 0.000537
koi_Kv42 = 0.0669
kio_Kv42 = 0.04246
vshift_Kv42 = -20
insert Cav22
gbar_Cav22 = 5e-05
insert Cav12
gbar_Cav12 = 1e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 2e-06
insert Cav32
gbar_Cav32 = 2.2e-05
insert SK2
gkbar_SK2 = 1.66667e-06
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
}
}
forsec cellList.o(CELLINDEX).regadendIML {
insert pas
cm = 1.0215
Ra = 200
g_pas = 1.57153e-05
e_pas = -70
insert Kir21
gkbar_Kir21 = 3.82215e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert HCN
cAMP_HCN = 0
e_HCN = -41.9
gbar_HCN = 4e-06
vhalfl_HCN = -100
kl_HCN = 8
vhalft_HCN = 30.4
at_HCN = 0.00052
bt_HCN = 0.2151
insert Kv42
gkbar_Kv42 = 0.002175
a0_Kv42 = 0.416
za_Kv42 = 1.1
b0_Kv42 = 0.0486
zb_Kv42 = -1.556
kco0_Kv42 = 0.347
zco_Kv42 = 0
koc0_Kv42 = 1.67
zoc_Kv42 = 0
kci_Kv42 = 0.04873
kic_Kv42 = 0.000537
koi_Kv42 = 0.0669
kio_Kv42 = 0.04246
vshift_Kv42 = -20
insert Cav22
gbar_Cav22 = 5e-05
hTau_Cav22 = 80
insert Cav12
gbar_Cav12 = 4e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 4e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 2.2e-05
insert SK2
gkbar_SK2 = 4.375e-06
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
}
forsec cellList.o(CELLINDEX).regadendMML {
insert pas
cm = 1.143
Ra = 200
g_pas = 1.75846e-05
e_pas = -70
insert Kir21
gkbar_Kir21 = 3.82215e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert HCN
cAMP_HCN = 0
e_HCN = -41.9
gbar_HCN = 4e-06
vhalfl_HCN = -100
kl_HCN = 8
vhalft_HCN = 30.4
at_HCN = 0.00052
bt_HCN = 0.2151
insert Kv42
gkbar_Kv42 = 0.002175
a0_Kv42 = 0.416
za_Kv42 = 1.1
b0_Kv42 = 0.0486
zb_Kv42 = -1.556
kco0_Kv42 = 0.347
zco_Kv42 = 0
koc0_Kv42 = 1.67
zoc_Kv42 = 0
kci_Kv42 = 0.04873
kic_Kv42 = 0.000537
koi_Kv42 = 0.0669
kio_Kv42 = 0.04246
vshift_Kv42 = -20
insert Cav22
gbar_Cav22 = 5e-05
hTau_Cav22 = 80
insert Cav12
gbar_Cav12 = 4e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 4e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 2.2e-05
insert SK2
gkbar_SK2 = 4.375e-06
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
}
forsec cellList.o(CELLINDEX).regadendOML {
insert pas
cm = 1.143
Ra = 200
g_pas = 1.75846e-05
e_pas = -70
insert Kir21
gkbar_Kir21 = 3.82215e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert HCN
cAMP_HCN = 0
e_HCN = -41.9
gbar_HCN = 4e-06
vhalfl_HCN = -100
kl_HCN = 8
vhalft_HCN = 30.4
at_HCN = 0.00052
bt_HCN = 0.2151
insert Kv42
gkbar_Kv42 = 0.002175
a0_Kv42 = 0.416
za_Kv42 = 1.1
b0_Kv42 = 0.0486
zb_Kv42 = -1.556
kco0_Kv42 = 0.347
zco_Kv42 = 0
koc0_Kv42 = 1.67
zoc_Kv42 = 0
kci_Kv42 = 0.04873
kic_Kv42 = 0.000537
koi_Kv42 = 0.0669
kio_Kv42 = 0.04246
vshift_Kv42 = -20
insert Cav22
gbar_Cav22 = 5e-05
hTau_Cav22 = 80
insert Cav12
gbar_Cav12 = 4e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 4e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 2.2e-05
insert SK2
gkbar_SK2 = 4.375e-06
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
}
forsec cellList.o(CELLINDEX).regaxon {
insert pas
cm = 0.9
Ra = 100
g_pas = 6.59341e-06
e_pas = -70
insert Kir21
gkbar_Kir21 = 1.82007e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert na8st
vShift_na8st = 22
vShift_inact_na8st = 0
a1_0_na8st = 62.6477
a1_1_na8st = 0.0116055
b1_0_na8st = 0.00193691
b1_1_na8st = 0.137719
a2_0_na8st = 34.7828
a2_1_na8st = 0.0299559
b2_0_na8st = 0.0957515
b2_1_na8st = 0.0928114
a3_0_na8st = 76.6983
a3_1_na8st = 0.0537432
b3_0_na8st = 1.24879
b3_1_na8st = 0.0311504
bh_0_na8st = 2.9807
bh_1_na8st = 0.4679
bh_2_na8st = 0.0596
ah_0_na8st = 0.3962
ah_1_na8st = 2982.1
ah_2_na8st = 0.0635
gbar_na8st = 0.066096
insert Kv11
gkbar_Kv11 = 0.00025
vshift_Kv11 = 0
insert Kv14
gkbar_Kv14 = 0.001
vshift_Kv14 = 0
insert Kv34
gkbar_Kv34 = 0.00765625
scale_a_Kv34 = 4
ksl_Kv34 = 0.5
insert Kv723
gkbar_Kv723 = 0.00067
Dtaumult1_Kv723 = 6
Dtaumult2_Kv723 = 6
tau0mult_Kv723 = 0.2
insert Cabuffer
brat_Cabuffer = 10
tau_Cabuffer = 43
insert Cav22
gbar_Cav22 = 5e-05
hTau_Cav22 = 80
insert Cav13
gbar_Cav13 = 2e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 8e-06
insert BK
gabkbar_BK = 0
gakbar_BK = 0.03744
diff_BK = 100000
base_BK = 4
insert SK2
gkbar_SK2 = 1.25e-05
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
}
forsec cellList.o(CELLINDEX).regaxonh {
insert pas
cm = 0.9
Ra = 200
g_pas = 6.59341e-06
e_pas = -70
insert Kir21
gkbar_Kir21 = 1.82007e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert na8st
vShift_na8st = 22
vShift_inact_na8st = 0
a1_0_na8st = 62.6477
a1_1_na8st = 0.0116055
b1_0_na8st = 0.00193691
b1_1_na8st = 0.137719
a2_0_na8st = 34.7828
a2_1_na8st = 0.0299559
b2_0_na8st = 0.0957515
b2_1_na8st = 0.0928114
a3_0_na8st = 76.6983
a3_1_na8st = 0.0537432
b3_0_na8st = 1.24879
b3_1_na8st = 0.0311504
bh_0_na8st = 2.9807
bh_1_na8st = 0.4679
bh_2_na8st = 0.0596
ah_0_na8st = 0.3962
ah_1_na8st = 2982.1
ah_2_na8st = 0.0635
gbar_na8st = 0.3888
insert Kv11
gkbar_Kv11 = 0.00025
vshift_Kv11 = 0
insert Kv14
gkbar_Kv14 = 0.001
vshift_Kv14 = 0
insert Kv34
gkbar_Kv34 = 0.0307813
scale_a_Kv34 = 4
ksl_Kv34 = 0.5
insert Kv723
gkbar_Kv723 = 0.00335
Dtaumult1_Kv723 = 6
Dtaumult2_Kv723 = 6
tau0mult_Kv723 = 0.2
insert Cav22
gbar_Cav22 = 5e-05
hTau_Cav22 = 80
insert Cav12
gbar_Cav12 = 1e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 4e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 8e-06
insert BK
gabkbar_BK = 0
gakbar_BK = 0.03744
diff_BK = 100000
base_BK = 4
insert SK2
gkbar_SK2 = 8.33333e-05
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
insert Cabuffer
brat_Cabuffer = 50
tau_Cabuffer = 240
depth_Cabuffer = 0.05
}
forsec cellList.o(CELLINDEX).regsoma {
insert pas
cm = 0.9
Ra = 200
g_pas = 1.38462e-05
e_pas = -70
insert Kir21
gkbar_Kir21 = 3.82215e-05
mg_i_Kir21 = 4
spm_i_Kir21 = 1
gsub_Kir21 = 0.25
fac_Kir21 = 0.005
vshiftbs_Kir21 = 0
vshiftbb_Kir21 = 0
b_Kir21 = 0.105
shiftmg_Kir21 = 0.5
cas_Kir21 = 0.142857
As_Kir21 = 0.2
insert na8st
vShift_na8st = 22
vShift_inact_na8st = 0
a1_0_na8st = 45.8498
a1_1_na8st = 0.0239354
b1_0_na8st = 0.0144095
b1_1_na8st = 0.0884761
a2_0_na8st = 19.8084
a2_1_na8st = 0.0221771
b2_0_na8st = 0.565017
b2_1_na8st = 0.061084
a3_0_na8st = 71.8119
a3_1_na8st = 0.0659379
b3_0_na8st = 0.753118
b3_1_na8st = 0.0364798
bh_0_na8st = 2.9713
bh_1_na8st = 0.6443
bh_2_na8st = 0.0594
ah_0_na8st = 1.586
ah_1_na8st = 2306.7
ah_2_na8st = 0.0493
gbar_na8st = 0.066096
insert Kv21
gkbar_Kv21 = 0.00354545
insert Cabuffer
brat_Cabuffer = 200
tau_Cabuffer = 240
insert Cav22
gbar_Cav22 = 0.0003
hTau_Cav22 = 80
insert Cav12
gbar_Cav12 = 2e-05
kf_Cav12 = 0.0005
insert Cav13
gbar_Cav13 = 8e-06
kf_Cav13 = 0.0005
insert Cav32
gbar_Cav32 = 2.2e-05
insert BK
gabkbar_BK = 0
gakbar_BK = 0.00936
diff_BK = 1.5
base_BK = 4
insert SK2
gkbar_SK2 = 8.33333e-07
diff_SK2 = 3
Q10_SK2 = 5
fac_SK2 = 2.5
diro2_SK2 = 0.1
invc3_SK2 = 0.09
invc1_SK2 = 0.32
invc2_SK2 = 0.32
dirc4_SK2 = 320
}
// ***** Now adjust number of segments *****
geom_nseg()
}