//genesis // kkit Version 11 flat dumpfile // Saved on Fri Jan 7 15:56:07 2011 include kkit {argv 1} FASTDT = 0.01 SIMDT = 0.001 CONTROLDT = 0.1 PLOTDT = 0.1 MAXTIME = 200 TRANSIENT_TIME = 2 VARIABLE_DT_FLAG = 0 DEFAULT_VOL = 1e-18 VERSION = 11.0 setfield /file/modpath value /home2/bhalla/scripts/modules kparms //genesis initdump -version 3 -ignoreorphans 1 simobjdump doqcsinfo filename accessname accesstype transcriber developer \ citation species tissue cellcompartment methodology sources \ model_implementation model_validation x y z simobjdump table input output alloced step_mode stepsize x y z simobjdump xtree path script namemode sizescale simobjdump xcoredraw xmin xmax ymin ymax simobjdump xtext editable simobjdump xgraph xmin xmax ymin ymax overlay simobjdump xplot pixflags script fg ysquish do_slope wy simobjdump group xtree_fg_req xtree_textfg_req plotfield expanded movealone \ link savename file version md5sum mod_save_flag x y z simobjdump geometry size dim shape outside xtree_fg_req xtree_textfg_req x y \ z simobjdump kpool DiffConst CoInit Co n nInit mwt nMin vol slave_enable \ geomname xtree_fg_req xtree_textfg_req x y z simobjdump kreac kf kb notes xtree_fg_req xtree_textfg_req x y z simobjdump kenz CoComplexInit CoComplex nComplexInit nComplex vol k1 k2 k3 \ keepconc usecomplex notes xtree_fg_req xtree_textfg_req link x y z simobjdump stim level1 width1 delay1 level2 width2 delay2 baselevel trig_time \ trig_mode notes xtree_fg_req xtree_textfg_req is_running x y z simobjdump xtab input output alloced step_mode stepsize notes editfunc \ xtree_fg_req xtree_textfg_req baselevel last_x last_y is_running x y z simobjdump kchan perm gmax Vm is_active use_nernst notes xtree_fg_req \ xtree_textfg_req x y z simobjdump transport input output alloced step_mode stepsize dt delay clock \ kf xtree_fg_req xtree_textfg_req x y z simobjdump proto x y z simobjdump text str simundump geometry /kinetics/geometry 0 9.9998e-19 3 sphere "" white black 0 \ 0 0 simundump text /kinetics/notes 0 "" call /kinetics/notes LOAD \ "" simundump kpool /kinetics/P_MAPK 1 1e-12 0 0 0 0 0 0 599.99 4 \ /kinetics/geometry red black 6 0 0 simundump text /kinetics/P_MAPK/notes 0 "" call /kinetics/P_MAPK/notes LOAD \ "" simundump kenz /kinetics/P_MAPK/phosph_KA 0 0 0 0 0 599.99 0.0083335 40 10 0 \ 0 "" red red "" 3 -2 0 simundump text /kinetics/P_MAPK/phosph_KA/notes 0 "" call /kinetics/P_MAPK/phosph_KA/notes LOAD \ "" simundump kpool /kinetics/K_A 0 0 1 1 600 600 0 0 600 0 /kinetics/geometry 25 \ black 1 -4 0 simundump text /kinetics/K_A/notes 0 \ "This is the unphosphorylated K_A channel, which has the\nfull channel conductance." call /kinetics/K_A/notes LOAD \ "This is the unphosphorylated K_A channel, which has the" \ "full channel conductance." simundump kpool /kinetics/P_K_A 0 0 0 0 0 0 0 0 600 0 /kinetics/geometry 52 \ black 5 -4 0 simundump text /kinetics/P_K_A/notes 0 "" call /kinetics/P_K_A/notes LOAD \ "" simundump kreac /kinetics/dephosph 0 0.05 0 "" white black 3 -6 0 simundump text /kinetics/dephosph/notes 0 "" call /kinetics/dephosph/notes LOAD \ "" simundump text /kinetics/geometry/notes 0 "" call /kinetics/geometry/notes LOAD \ "" simundump xgraph /graphs/conc1 0 0 443 1e-06 0.92797 0 simundump xgraph /graphs/conc2 0 0 443 0 0.01528 0 simundump xplot /graphs/conc2/P_MAPK.Co 3 524288 \ "delete_plot.w <s> <d>; edit_plot.D <w>" red 0 0 1 simundump xplot /graphs/conc2/K_A.Co 3 524288 \ "delete_plot.w <s> <d>; edit_plot.D <w>" 25 0 0 1 simundump xgraph /moregraphs/conc3 0 0 443 0 4 0 simundump xgraph /moregraphs/conc4 0 0 443 0 4 0 simundump xcoredraw /edit/draw 0 -2 12 -8 9 simundump xtree /edit/draw/tree 0 \ /kinetics/#[],/kinetics/#[]/#[],/kinetics/#[]/#[]/#[][TYPE!=proto],/kinetics/#[]/#[]/#[][TYPE!=linkinfo]/##[] \ "edit_elm.D <v>; drag_from_edit.w <d> <S> <x> <y> <z>" auto 0.6 simundump xtext /file/notes 0 1 xtextload /file/notes \ "7 Jan 2011" \ "Skeleton model to test KA effect on electrica properties of model" \ "CA1 neuron." addmsg /kinetics/P_MAPK/phosph_KA /kinetics/P_MAPK REAC eA B addmsg /kinetics/P_MAPK /kinetics/P_MAPK/phosph_KA ENZYME n addmsg /kinetics/K_A /kinetics/P_MAPK/phosph_KA SUBSTRATE n addmsg /kinetics/dephosph /kinetics/K_A REAC B A addmsg /kinetics/P_MAPK/phosph_KA /kinetics/K_A REAC sA B addmsg /kinetics/dephosph /kinetics/P_K_A REAC A B addmsg /kinetics/P_MAPK/phosph_KA /kinetics/P_K_A MM_PRD pA addmsg /kinetics/P_K_A /kinetics/dephosph SUBSTRATE n addmsg /kinetics/K_A /kinetics/dephosph PRODUCT n addmsg /kinetics/P_MAPK /graphs/conc2/P_MAPK.Co PLOT Co *P_MAPK.Co *red addmsg /kinetics/K_A /graphs/conc2/K_A.Co PLOT Co *K_A.Co *25 enddump // End of dump call /kinetics/K_A/notes LOAD \ "This is the unphosphorylated K_A channel, which has the" \ "full channel conductance." complete_loading