TITLE Inward rectifying Potassium current
COMMENT
Used in Role of a Striatal Slowly Inactivating Potassion Current in Short-term
Facilitation of Corticostriatal Inputs" A computer Simulation Study" (Mahon et al. 2000)
Implemented by Kevin M. Biddell kevin.biddell@gmail.com
7/12/06
note: activation is instantaneous but we will assume for implementation purposes that the mtau is small enough to simulate this behavior on our time scale
NOTE: 1S=1mho Neuron wants the units in mhos not millisiemens, please note the conversion!
ENDCOMMENT
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
NEURON {
SUFFIX Kirm
USEION k WRITE ik
RANGE gkirmbar, gkirm, minf
}
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
PARAMETER {
ek = -90 (mV)
gkirmbar= 0.0002 (mho/cm2) :changed from 0.00015 by KMB
tau = 0.01 (ms)
Vsm = -100
ksm = -10
}
STATE {
m
}
ASSIGNED {
v (mV)
ik (mA/cm2)
celsius (degC)
minf
mtau
gkirm
}
BREAKPOINT {
SOLVE states METHOD cnexp
gkirm = gkirmbar*m
ik = gkirm*(v - ek)
}
UNITSOFF
INITIAL {
rates(v)
m= minf
}
DERIVATIVE states { :Computes states variable m at the current v and dt.
rates(v)
m' = ( minf - m ) / mtau
}
PROCEDURE rates(v) { :Computes rate and other constants at current v.
:Call once from HOC to initialize inf at resting v.
: The activation is instantaneous therefore not temperature dependent
minf=1/(1+exp(-(v-Vsm)/ksm))
mtau=tau
}
UNITSON