/*--------------------------------------------------------
Insert passive and active properties in rc19 cell.
Option to have non-uniform resting Vm in basal dendrites
Tiago Branco (2010)
--------------------------------------------------------*/
proc init_params() {
celsius = 37
Cm = 1
Rm = 10000
Ri = 150
v_init = -75
}
//-------------------------------------------------------
//add passive properties
//-------------------------------------------------------
proc init_passive(){
forall {insert pas g_pas = 1/Rm e_pas=v_init cm=Cm Ra=Ri}
axon {g_pas = 0.02}
}
proc nonunif_rm(){
a = $1
dendid = $2
x=1
access dend[dendid]
for(x,0) {
gm = 1/Rm*(1+2*a*(x-1/2))
g_pas(1-x) = gm
}
}
//-------------------------------------------------------
//add active properties
//-------------------------------------------------------
proc init_active_params(){
Ek = -90
Ena = 60
Eca = 140
vshift_na = -5
vshift_ca = 0
gna_axon = 30000
gkv_axon = 400
gna_soma = 1500
gkv_soma = 200
gkm_soma = 2.2
gkca_soma = 2.5
gca_soma = 0.5
git_soma = 0.0003
gna_dend = 40
gkv_dend = 30
gkm_dend = 0.05
gkca_dend = 2.5
gca_dend = 0.5
git_dend = 0.0006
gh_dend = 0
}
proc init_active(){
forsec axonal {
insert na gbar_na = gna_axon
insert kv gbar_kv = gkv_axon
}
forsec somatic {
insert na gbar_na = gna_soma
insert kv gbar_kv = gkv_soma
insert km gbar_km = gkm_soma
insert kca gbar_kca = gkca_soma
insert ca gbar_ca = gca_soma
insert it gbar_it = git_soma
}
forsec basal {
insert na gbar_na = gna_dend
insert kv gbar_kv = gkv_dend
insert km gbar_km = gkm_dend
insert kca gbar_kca = gkca_dend
insert ca gbar_ca = gca_dend
insert it gbar_it = git_dend
insert hd ghdbar_hd = gh_dend
}
forall if(ismembrane("k_ion")) ek = Ek
forall if(ismembrane("na_ion")) ena = Ena
forall if(ismembrane("ca_ion")) {
ion_style("ca_ion",0,1,0,0,0)
vshift_ca = 0
}
}