NEURON {
SUFFIX kd
USEION k READ ek WRITE ik
RANGE gkd, g
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
q10=3
gkd = 0.00039 (S/cm2)
theta_a = -50 (mV) :-50
sigma_a = 20 (mV)
theta_b = -70 (mV)
sigma_b = -6 (mV)
tau_a = 1.4 (ms) :2,1.4
tau_b = 150 (ms)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
g (S/cm2)
qt
}
STATE {a b}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gkd * a^3 * b
ik = g * (v-ek)
}
INITIAL {
a = ainfi(v)
b = binfi(v)
qt = 3^((celsius - 24)/10)
:tau_a = 2/qt :1.4
:tau_b = 350/qt:150
}
DERIVATIVE states {
a' = (ainfi(v)-a)/tau_a
b' = (binfi(v)-b)/tau_b
}
FUNCTION ainfi(v (mV)) {
UNITSOFF
ainfi=1/(1 + exp(-(v-theta_a)/sigma_a))
UNITSON
}
FUNCTION binfi(v (mV)) {
UNITSOFF
binfi=1/(1 + exp(-(v-theta_b)/sigma_b))
UNITSON
}