Instructions it is attached. Please unpack the archive. Then use the Terminal to go to the DSB94 directory and say nrnivmodl nrngui DS2M0Purk.hoc This is an example run and will generate the voltage response to a 1000 ms, 1.5 nA current pulse at the soma. Let me know if you have questions how to modify the run() and metarun() procedures to suit our needs.