// create subset that contains only the apicals and the soma
objref atree
atree = new SectionList()
soma atree.append()
apic[0] atree.subtree()
// show just the elements of the set in a Shape
objref atreesh
atreesh = new Shape(0)
atreesh.size(-10,740,-429.402,319.402)
atreesh.view(-10, -429.402, 750, 748.804, 7, 105, 200.64, 200.32)
atreesh.observe(atree)
// build subsets that contain cal+can and car+cat
// note the model no longer uses uses this type of ca distrib.
// however this portion of the code still needs to be cleaned up.
objref calcan, carcat
calcan = new SectionList()
carcat = new SectionList()
forsec atree {
if (ismembrane("cal")) {
calcan.append()
} else {
// these are nonoverlapping, so . . .
carcat.append()
}
}
forsec atree {
insert caquant
for (x,0) svr_caquant(x) = 1/depth_cacum(x)
}
mode_caquant = 1 // measure peak ica and cai
proc xrun() {
finitialize(v_init)
mode_caquant = 1 // measure peak ica and cai
run() // don't bother with runm()--does lots of stuff not
// relevant to these figs
// note: the use of different slightly different initializations
// for example, the one from init() in init_and_run....hoc, can
// lead to especially different half widths of the ica spike as the
// AP backpropagates into the distal dendrites. However the basic
// result that the max calcium peak occurs in the obliques
// proximal to the branch from the trunk remains unchanged in both the
// control and aBeta cases (as long as there is significant propagation
// into that proximal portion of the oblique).
mode_caquant = 2
run()
/*
Sets up plots of max ica, cai, max cai, ica halfwidth,
surface/vol ratio, approx q entry by ca, and predicted max cai.
Also sets up a List of the cmax range var plots
and a List of the SectionLists that define the spatial coverage
of each RangeVarPlot.
*/
load_file("maxica.hoc")
}
// apply abeta before calling the following procs
// show recording sites
MARKSIZE = 4 // size of marks. 4 is good for small Shapes
proc show_recording_sites() {
// markpoints.hoc presumes maxica.hoc has been loaded
load_file("maxica.hoc")
load_file("markpoints.hoc") // to mark points on a shape plot
domarks(atreesh, MARKSIZE) // atreesh or shlist.o(i) where i=0-3 (tuft, dist, intermed, prox)
}
// show time axis plots of v, i, can caimax
// these would look better if tstop were 15 ms
// throw away after generating plots
proc vicaplots() { local tsave
xopen("proxplots.ses")
xopen("intermedplots.ses")
xopen("distplots.ses")
xopen("tuftplots.ses")
xrun()
}
proc myshapes() { local ii
load_file("maxica.hoc")
pathshapes()
atreesh.exec_menu("View Axis")
// shlist is empty when this proc is first parsed
// so we can't do this:
// for ii=0,shlist.count()-1 shlist.o(ii).exec_menu("View Axis")
// but we can get away with this:
execute("for ii=0,shlist.count()-1 shlist.o(ii).exec_menu(\"View Axis\")")
}