load_file("nrngui.hoc")
load_file("../template/load_templates.hoc")
strdef accstr // not confuse experimental variable bindings with neurophysiological variable bindings
objref econ // Create an experiment object
show_errs=1
debug_lev=1
econ=new ExperimentControl(show_errs,debug_lev)
econ.self_define(econ) // points the object at itself
econ.morphology_dir = "../morphology/n123" // Setup morphology directory
econ.generic_dir = "../experiment/" // Setup directory with cell-setup file
econ.add_lib_dir("Terrence","../lib") // Setup directory with library functions
if (unix_mac_pc() ==1 ) {
econ.data_dir = "data" // Define directory to save produced data
sprint(econ.syscmd, "mkdir -p %s", econ.data_dir) // make the data directory
system(econ.syscmd)
}
// *******************************************************
// Setup cell
// *******************************************************
objref dendrv
dendrv = new Vector(0)
// Define spine position
dendr = 3
spinepos = 0.1
// Define spine geometry
neckW = 0.147
neckL = 0.667
headW = 0.519
headL = 0.519
econ.xopen_geometry_dependent("cell_+spine") // load the raw cell morphology
econ.xopen_geometry_dependent("cell-analysis") // load user-defined semantics on morphology
cell_analysis(econ)
printf("Opening cell setup\n")
econ.xopen_generic("cell-setup_regular") // load the cell-setup file (define specific
printf("Opened. Setting up cell\n") // channels, membrane properties etc)
cell_setup(econ)
// *******************************************************
// Set simulation parameters
// *******************************************************
econ.defvar("Simulation Control", "tstop", "30", "Defines when the simulation stops.")
econ.defvar("Simulation Control", "dt", "0.025", "Timestep") // 0.1 originally
econ.defvar("Simulation Control", "steps_per_ms", "40", "How many points are plotted per ms")
setdt()
// *******************************************************
// Set maximum segment length 5um and nseg = odd multiple of 5
// *******************************************************
for i=0,118 {
apical_dendrite[i] {nseg=int((int(L/5)+5)/10)*10+5}
}
// *******************************************************
// Initialize experiment
// *******************************************************
nrnmainmenu()
access soma
v_init = -70
forall {insert cldifus}
forall {Ra = 100}
finitialize(v_init)
fcurrent()