TITLE H-current
NEURON {
SUFFIX h
RANGE gbar,vhalf, K, taun, ninf, g :range variables
USEION na READ ena WRITE ina : which ions to use and how to treat them ena = reversal pot for Na
: NONSPECIFIC_CURRENT i
}
UNITS {
(um) = (micrometer)
(mA) = (milliamp)
(uA) = (microamp)
(mV) = (millivolt)
(pmho) = (picomho)
(mmho) = (millimho)
}
INDEPENDENT {t FROM 0 TO 1 WITH 100 (ms)}
PARAMETER { : parameters that can be entered when function is called in cell-setup
dt (ms)
v (mV)
ena=0 (mV)
K = 8.5 (mV)
gbar = 0.1 (mmho/cm2) : this is the somatic value. dendritic value is 6x higher
vhalf =-90 (mV)
}
STATE { : the unknown parameters to be solved in the DEs
n
}
ASSIGNED { : parameters neede to solve DE
ina (mA/cm2)
ninf
taun (ms)
g
}
INITIAL { : initialize the following parameter using states()
states()
n = ninf
g = gbar*n
ina = g*(v-ena)*(0.001)
}
BREAKPOINT {
SOLVE h METHOD derivimplicit
g = gbar*n
ina = g*(v-ena)*(0.001)
}
DERIVATIVE h {
states()
n' =(ninf - n)/taun
}
PROCEDURE states() {
if (v > -30) {
taun = 1
} else {
: taun = -0.5(ms/mV)*v - 10(ms)
taun = -0.5(ms/mV)*v - 10(ms)
}
ninf = 1 - (1 / (1 + exp((vhalf - v)/K)))
}