TITLE Borg-Graham type generic K-AHP channel
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
celsius (degC)
gkahpbar=.003 (mho/cm2)
n=4
cai=50.e-6 (mM)
a0=1.3e13 (/ms-mM-mM-mM-mM) :b0/(1.4e-4^4)
b0=.5e-2 (/ms) :0.5/(0.100e3)
v (mV)
ek (mV)
}
NEURON {
SUFFIX kahp
USEION k READ ek WRITE ik
USEION ca READ cai
RANGE gkahpbar,gkahp
GLOBAL inf,tau
}
STATE {
w
}
ASSIGNED {
ik (mA/cm2)
gkahp (mho/cm2)
inf
tau
}
INITIAL {
rate(cai)
w=inf
}
BREAKPOINT {
SOLVE state METHOD cnexp
gkahp = gkahpbar*w
ik = gkahp*(v-ek)
}
FUNCTION alp(cai (mM)) {
alp = a0*cai^n
}
DERIVATIVE state { : exact when v held constant; integrates over dt step
rate(cai)
w' = (inf - w)/tau
}
PROCEDURE rate(cai (mM)) { :callable from hoc
LOCAL a
a = alp(cai)
tau = 1/(a + b0)
inf = a*tau
}