TITLE Persistent sodium current (NaP) of deep cerebellar nucleus (DCN) neuron
COMMENT
Translated from GENESIS by Johannes Luthman and Volker Steuber.
ENDCOMMENT
NEURON {
SUFFIX NaP
USEION na READ ena WRITE ina
RANGE gbar, ina, m, h
GLOBAL qdeltat
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
qdeltat = 1
gbar = 1e-5 (siemens/cm2)
}
ASSIGNED {
v (mV)
ena (mV)
ina (mA/cm2)
minf
hinf
taum (ms)
tauh (ms)
}
STATE {
m
h
}
INITIAL {
rate(v)
taum = 50 / qdeltat
m = minf
h = hinf
}
BREAKPOINT {
SOLVE states METHOD cnexp
ina = gbar * m*m*m * h * (v - ena)
}
DERIVATIVE states {
rate(v)
m' =(minf - m)/taum
h' =(hinf - h)/tauh
}
PROCEDURE rate(v(mV)) {
TABLE minf, hinf, tauh FROM -150 TO 100 WITH 300
minf = 1 / (1 + exp((v + 70) / -4.1))
hinf = 1 / (1 + exp((v + 80) / 4))
tauh = (1750 / (1 + exp((v + 65) / -8))) + 250
tauh = tauh / qdeltat
}