COMMENT
Kinetic model of synaptic transmission
dr/dt = (rinf(T)-r)/taur(T)
i = g * r * ( v - e )
ENDCOMMENT
NEURON {
POINT_PROCESS KineticSynapse
RANGE onset, duration, tau1, tau2, gmax, e, i
NONSPECIFIC_CURRENT i
}
UNITS {
(nA) = (nanoamp)
(mV) = (millivolt)
(uS) = (microsiemens)
}
PARAMETER {
onset=0 (ms)
duration=1 (ms)
tau1=0.1 (ms)
tau2=5 (ms)
gmax=0 (uS)
e=0 (mV)
}
ASSIGNED {
v (mV)
i (nA)
g (uS)
}
STATE {
r
}
BREAKPOINT {
if (gmax) {
at_time( onset )
at_time( onset + duration )
}
SOLVE state METHOD cnexp
i = gmax * r * ( v - e )
}
UNITSOFF
INITIAL {
r = 0
}
DERIVATIVE state {
r' = ( 1.0 / tau1 - 1.0 / tau2 ) * T( t ) * ( 1.0 - r ) - r / tau2
}
FUNCTION T( t ) {
if ( t < onset || t > onset + duration ) {
T = 0
} else {
T = 1
}
}
UNITSON