#!/bin/perl
#*****************************************************
# A simple model of a single AZ at the calyx of Held *
# *
# This script runs one simulation *
# and can be passed to individual nodes in *
# simulations using condor. *
# *
# This script takes two parameters, the first is the *
# identification number of the simulation ($simid *
# in prepare_simulation_script.pl) and the second *
# the random seed for the current simulation *
# ($run in prepare_simulation_script.pl) *
# *
# *
# Matthias Hennig *
# mhennig@inf.ed.ac.uk *
#*****************************************************
print "running simulation: @ARGV[0], @ARGV[1]\n";
system "/bin/rm", "-f", "chkpt_pos";
$simid = @ARGV[0];
$run = @ARGV[1];
# prepare the file that contains the fusion pore dimension
open(PS, ">pore_scale");
print PS "check_time = 5\n";
print PS "abs_time = 5\n";
close(PS);
# adjust this:
$prg = "/home/mhennig/bin/mcell";
# the gradual opening of the fusion pore is approximated by changing the diamater
# every 5\mu s
for ( $chk = 1; $chk <= 61; $chk++) {
system $prg, "-seed $run", "calyx_@ARGV[0]\_@ARGV[1].mdl";
# adist the pore if time < 300\mu s
if ( $chk < 60 ) {
open(PS, ">pore_scale");
print PS "check_time = 5\n";
$at = $chk*5+5;
print PS "abs_time = $at\n";
close(PS);
} else { # or run the rest of the simulation with a constant maximal pore diameter
open(PS, ">pore_scale");
print PS "check_time = 3000\n";
print PS "abs_time = 3000\n";
close(PS);
}
}