COMMENT
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
//
// NOTICE OF COPYRIGHT AND OWNERSHIP OF SOFTWARE
//
// Copyright 2007, The University Of Pennsylvania
// School of Engineering & Applied Science.
// All rights reserved.
// For research use only; commercial use prohibited.
// Distribution without permission of Maciej T. Lazarewicz not permitted.
// mlazarew@seas.upenn.edu
//
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
This mode file is based on the paper:
Tort, A. B., Rotstein, H. G., Dugladze, T., et al. (2007). On the formation of gamma-coherent cell
assemblies by oriens lacunosum-moleculare interneurons in the hippocampus. Proc Natl Acad Sci U S A.
ENDCOMMENT
NEURON {
SUFFIX IhPyrKop
NONSPECIFIC_CURRENT i
RANGE v50, gmax
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(mS) = (millisiemens)
}
PARAMETER {
gmax = 0.0 (mS/cm2)
eh = -30.0 (mV)
v50 = 0.0 (mV)
}
ASSIGNED {
v (mV)
i (mA/cm2)
}
STATE { q }
INITIAL { q = qinf(v) }
BREAKPOINT {
SOLVE states METHOD cnexp
i = (1e-3) * gmax * q * (v-eh)
}
DERIVATIVE states { q' = (qinf(v)-q)/qtau(v) }
FUNCTION qinf(v(mV)) { qinf = fun2(v, v50, 1.0, 10.5)*1.0(ms) }
FUNCTION qtau(v(mV))(ms) { qtau = 1.0(ms)/(exp((-14.59(mV)-0.086*v)/1.0(mV)) + exp((-1.87(mV)+0.0701*v)/1.0(mV))) }
:HCN1
:FUNCTION qinf(v(mV)) { qinf = fun2(v, v50, 1, 1.0/0.151)*1(ms) }
:FUNCTION qtau(v(mV))(ms) { qtau = exp(0.033(/mV)*(v+75))/(0.011*(1+exp(0.083(/mV)*(v+75))))*1(ms)}
INCLUDE "aux_fun.inc"