COMMENT
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
//
// NOTICE OF COPYRIGHT AND OWNERSHIP OF SOFTWARE
//
// Copyright 2007, The University Of Pennsylvania
// School of Engineering & Applied Science.
// All rights reserved.
// For research use only; commercial use prohibited.
// Distribution without permission of Maciej T. Lazarewicz not permitted.
// mlazarew@seas.upenn.edu
//
//%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
ENDCOMMENT
NEURON {
SUFFIX kahppr
USEION k WRITE ik
USEION ca READ cai
RANGE gkahp, ik, qinf, tauq
}
UNITS {
(mollar) = (1/liter)
(mM) = (millimollar)
(mA) = (milliamp)
(mV) = (millivolt)
(mS) = (millisiemens)
}
PARAMETER {
gkahp = 0.8 (mS/cm2)
ek = -75 (mV)
}
ASSIGNED {
v (mV)
ik (mA/cm2)
cai (mM)
qinf (1)
tauq (ms)
}
STATE { q }
INITIAL {
rates(v)
q = qinf
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = (1e-3) * gkahp * q * (v-ek)
}
DERIVATIVE states {
rates(v)
q' = (qinf-q)/tauq
}
PROCEDURE rates(v(mV)) { LOCAL a,b
a = 0.01(/ms) * min(cai/500(mM),1)
b = 1(/ms)/1000
qinf = a/(a+b)
tauq = 1.0/(a+b)
}
INCLUDE "aux_fun.inc"