TITLE intracellular Calcium concentration dynamic
: from BEELER & REUTER, J.Physiol, 1977
COMMENT
Cardiac intracellular calcium
ENDCOMMENT
NEURON {
THREADSAFE
SUFFIX Cadynam
USEION ca READ ica, cai WRITE cai
USEION cs READ ics VALENCE 2
RANGE ics
}
UNITS {
(mM) = (milli/liter)
(mA) = (milliamp)
}
ASSIGNED{
ica (mA/cm2)
ics (mA/cm2)
}
PARAMETER {
}
STATE {
cai START 0.001 (mM) <1e-6>
}
INITIAL {
VERBATIM
cai = _ion_cai;
ENDVERBATIM
}
BREAKPOINT {
SOLVE state METHOD derivimplicit
}
DERIVATIVE state {
cai' = -1e-7*ics+0.07*(1e-7-cai)
}