TITLE Sodium ion accumulation
: Intracellular sodium ion accumulation
NEURON {
THREADSAFE
SUFFIX Na_acc
USEION na READ ina,nai WRITE nai
RANGE Vi, Naneutral : electroneutral sodium accumulation
}
UNITS {
(mV) = (millivolt)
(um) = (micron)
(mM) = (milli/liter)
(mA) = (milliamp)
F = (faraday) (coulombs)
}
PARAMETER {
Naneutral = 3e-5 (mA/cm2) <0,1e6>
Vi = 1.3668e-08 (cm3)
ina (mA/cm2)
}
STATE {
nai START 9.19 (mM)
}
LOCAL ViF
INITIAL {
VERBATIM
nai = _ion_nai;
ENDVERBATIM
ViF = F*Vi*2e4
}
BREAKPOINT {
SOLVE state METHOD derivimplicit
}
DERIVATIVE state {
nai' = -(ina-Naneutral)/(ViF)
}