# CelegansInterMotorNeuronsModels The folder contains the codes for reproducing the figures of the papers: Biophysical modeling of the whole-cell dynamics of C. elegans motor and interneurons families by M. Nicoletti et al. *PloS ONE*, 19(3): e0298105. [https://doi.org/10.1371/journal.pone.0298105](https://doi.org/10.1371/journal.pone.0298105) The repository contains python codes and NEURON `.mod` files for Hodgkin-Huxley models of AVAL, AVAR, VA5, VB6, VD5, AIY, and RIM C.elegans neurons. The `.mod` files allow to model 22 ionic currents and the intracellular calcium. The Python files are organized for each neuron (AVAL, AVAR, AIY, RIM, VA5, VB6, VD5) as follows: 1. file for simulating voltage and current clamp responses entitled "`NeuronName_simulation.py`" 2.two files containing the functions for voltage and current clamp protocols entitled "`NeuronName_simulation_vclamp.py`" and "`NeuronName_simulation_iclamp.py`", respectively To reproduce the WT whole-cell behavior: 1. compile the NEURON `.mod` files in the same folder of the python codes 2. excute the file "`NeuronName_simulation.py`" To simulate knock-out responses set to zero the conductance of the corresponding current.