{load_file("stdlib.hoc")}
celsius=36
{load_file("soma.hoc")}
access soma
///// Conductance changes required to produce an additive effect in the calcium concentration in the second voltage ramp /////
//gcaca_jcal = 0.01e-4
//taur_jcal = 10e1
//gbar_can = 4e-2
//integration time step
dt = 0.01
tstop = 12200
//inserting current clamp at soma
access soma
objectvar stim
stim = new jSEClamp(0.5)
stim.dur1 = 100
stim.amp1 = -80
stim.dur2 = 4000
stim.amp2 = -120
stim.dur3 = 2000
stim.amp3 = 0
stim.rs = 4
//for writing result files
objref vrec[1]
vrec[0] = new Vector()
{vrec[0].record(&stim.i, dt)}
objref tvec
tvec = new Vector()
{tvec.record(&t, dt)}
objref all
all = new File()
strdef datei
//graph
objref gmem
gmem = new Graph()
gmem.size(0, tstop, -2, 2)
{gmem.addvar("Membrane current", &stim.i, 2, 1)}
gmem.begin()
//defining some functions
proc run_sn() {
sprint(datei, "fig5currents.txt")
all.wopen(datei)
soma v = -55
finitialize()
while (t < tstop) {
fadvance()
all.printf("%g %g %g %g %g %g %g %g %g %g %g\n", t, cai, jina13_nav13, jina17_nav17, ica, jikdr_kdr, jika_ka, jikcaf_kca_fast, iother2, jikcas_kca_slow, jiih_ih)
gmem.plot(t)
}
gmem.flush()
all.close
write_file()
}
proc write_file() {
sprint(datei, "./fig5mem.txt")
all.wopen(datei)
for i=0, vrec[0].size()-1 {
all.printf("%g %g\n", tvec.x(i), vrec[0].x(i))
}
all.close
}
run_sn()
//quit()