clear
clc
close all
numsims=27;
numfull=3;
branges=cell(1, numsims/numfull);
bstart=2444;
bstartcsv=bstart;
for i=1:numsims/numfull
branges{i}=bstart+(i-1)*numfull:(bstart+numfull-1)+(i-1)*numfull;
end
close all
for i=1:numsims/numfull
brange=branges{i};
%% File names
load('progress_postpulse_2444to2470.mat');
load('progress_prepulse_2444to2470.mat');
%% Parameters
numcells=500;
endtime=2000;
pulsetime=1000;
dt=.01;
steps=endtime/dt+1;
% brange=106:105;
numgsyn=12;
numI=51;
loopnum=numgsyn*numI;
%% Construct Full Parameter Regime From Smaller Runs
Synchrony_full=zeros(numI+1, numgsyn+1);
popfreq_full=zeros(numI+1, numgsyn+1);
count=1;
for b=brange
temp=csvread(csvname{1+b-bstartcsv,1});
for k=1:(length(temp)/numI)
Synchrony_full(1:numI, count)=temp((1+(k-1)*numI):(k*numI));
count=count+1;
end
end
count=1;
for b=brange
temp2=csvread(csvname{1+b-bstartcsv,2});
for k=1:(length(temp2)/numI)
popfreq_full(1:numI, count)=temp2((1+(k-1)*numI):(k*numI));
count=count+1;
end
end
%% Input data from csv files
b=brange(1);
current=cd;
cd('/Users/scottrich/OneDrive - UHN/1) Compute Canada Files');
% cd('E:\OneDrive - UHN\1) Compute Canada Files');
str1=sprintf('InhibitoryNetwork_%d_TrackVariables.csv', b);
str2=sprintf('InhibitoryNetwork_%d_SpikeTimes.csv', b);
str3=sprintf('InhibitoryNetwork_%d_InputCurrents.csv', b);
str4=sprintf('InhibitoryNetwork_%d_ConnectivityMatricies.csv', b);
str5=sprintf('InhibitoryNetwork_%d_Parameters.csv', b);
% trackvariables=csvread(str1);
% spikes=csvread(str2);
% currents=csvread(str3);
% connectivity=csvread(str4);
variables=csvread(str5);
cd(current);
csvname4=sprintf('Synchrony_postpulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
csvname3=sprintf('PopulationFreq_postpulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
csvwrite(csvname4,Synchrony_full);
csvwrite(csvname3,popfreq_full);
%% Plot Full Parameter Regime
figure('units','normalized','position',[0 0 1 1])
colormap jet
subaxis(1,2,1, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingLeft', 0.07, 'PaddingRight', 0.01);
pcolor(Synchrony_full)
caxis([0 1])
colorbar
xlabels=0.25:.5:3;
ylabels=150:20:400;
set(gca,'TickDir','out')
set(gca,'box','off')
set(gca, 'XTick', 1.5:2:12.5);
set(gca, 'XTickLabel', xlabels);
set(gca, 'YTick', 1.5:4:51.5);
set(gca, 'YTickLabel', ylabels);
xtickangle(45)
ytickangle(45)
set(gca, 'FontSize', 20);
% ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
ylabel('External Applied Current (pA)', 'FontSize', 26)
title('Synchrony Measure', 'FontSize', 30);
subaxis(1,2,2, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingRight', 0.01, 'PaddingLeft', 0.05);
pcolor(popfreq_full)
caxis([0 200])
colorbar
set(gca,'TickDir','out')
set(gca,'box','off')
set(gca, 'XTick', 1.5:2:20.5);
set(gca, 'XTickLabel', xlabels);
set(gca, 'YTick', []);
set(gca, 'YTickLabel', ylabels);
xtickangle(45)
ytickangle(45)
set(gca, 'FontSize', 20);
% ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
% ylabel('External Applied Current (pA)', 'FontSize', 26)
title('Mean Firing Frequency (Hz)', 'FontSize', 30);
supAxis=[.0750 .10 .85 .85];
str1= sprintf('Inhibitory Synaptic Weight (nS)');
str3= sprintf('Connectivity Density: %1.2f; State: %1.0f; Post-Pulse', variables(1,1), variables(1,5));
[ax,h]=suplabel(str1, 'x', supAxis);
set(h, 'FontSize', 26);
[ax3,h3]=suplabel(str3, 't', supAxis);
set(h3, 'FontSize', 20);
str1=sprintf('Zoom_postpulse_state%d_probii%1.0f_std%1.0f_num%dto%d.png', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
% saveas(gcf, str1)
set(gcf,'PaperPositionMode','auto')
print(str1, '-dpng', '-r0');
%% Construct Full Parameter Regime From Smaller Runs PRE PULSE
Synchrony_full=zeros(numI+1, numgsyn+1);
popfreq_full=zeros(numI+1, numgsyn+1);
count=1;
for b=brange
temp=csvread(csvname2{1+b-bstartcsv,1});
for k=1:(length(temp)/numI)
Synchrony_full(1:numI, count)=temp((1+(k-1)*numI):(k*numI));
count=count+1;
end
end
count=1;
for b=brange
temp2=csvread(csvname2{1+b-bstartcsv,2});
for k=1:(length(temp2)/numI)
popfreq_full(1:numI, count)=temp2((1+(k-1)*numI):(k*numI));
count=count+1;
end
end
%% Input data from csv files
b=brange(1);
current=cd;
cd('/Users/scottrich/OneDrive - UHN/1) Compute Canada Files');
% cd('E:\OneDrive - UHN\1) Compute Canada Files');
str1=sprintf('InhibitoryNetwork_%d_TrackVariables.csv', b);
str2=sprintf('InhibitoryNetwork_%d_SpikeTimes.csv', b);
str3=sprintf('InhibitoryNetwork_%d_InputCurrents.csv', b);
str4=sprintf('InhibitoryNetwork_%d_ConnectivityMatricies.csv', b);
str5=sprintf('InhibitoryNetwork_%d_Parameters.csv', b);
% trackvariables=csvread(str1);
% spikes=csvread(str2);
% currents=csvread(str3);
% connectivity=csvread(str4);
variables=csvread(str5);
cd(current);
csvname4=sprintf('Synchrony_prepulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
csvname3=sprintf('PopulationFreq_prepulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
csvwrite(csvname4,Synchrony_full);
csvwrite(csvname3,popfreq_full);
%% Plot Full Parameter Regime
figure('units','normalized','position',[0 0 1 1])
colormap jet
subaxis(1,2,1, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingLeft', 0.07, 'PaddingRight', 0.01);
pcolor(Synchrony_full)
caxis([0 1])
colorbar
xlabels=0.25:.5:3;
ylabels=150:20:400;
set(gca,'TickDir','out')
set(gca,'box','off')
set(gca, 'XTick', 1.5:2:12.5);
set(gca, 'XTickLabel', xlabels);
set(gca, 'YTick', 1.5:4:51.5);
set(gca, 'YTickLabel', ylabels);
xtickangle(45)
ytickangle(45)
set(gca, 'FontSize', 20);
% ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
ylabel('External Applied Current (pA)', 'FontSize', 26)
title('Synchrony Measure', 'FontSize', 30);
subaxis(1,2,2, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingRight', 0.01, 'PaddingLeft', 0.05);
pcolor(popfreq_full)
caxis([0 200])
colorbar
set(gca,'TickDir','out')
set(gca,'box','off')
set(gca, 'XTick', 1.5:2:20.5);
set(gca, 'XTickLabel', xlabels);
set(gca, 'YTick', []);
set(gca, 'YTickLabel', ylabels);
xtickangle(45)
ytickangle(45)
set(gca, 'FontSize', 20);
% ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
% ylabel('External Applied Current (pA)', 'FontSize', 26)
title('Mean Firing Frequency (Hz)', 'FontSize', 30);
supAxis=[.0750 .10 .85 .85];
str1= sprintf('Inhibitory Synaptic Weight (nS)');
str3= sprintf('Connectivity Density: %1.2f; State: %1.0f; Pre-Pulse', variables(1,1), variables(1,5));
[ax,h]=suplabel(str1, 'x', supAxis);
set(h, 'FontSize', 26);
[ax3,h3]=suplabel(str3, 't', supAxis);
set(h3, 'FontSize', 20);
str1=sprintf('Zoom_prepulse_state%d_probii%1.0f_std%1.0f_num%dto%d.png', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
% saveas(gcf, str1)
set(gcf,'PaperPositionMode','auto')
print(str1, '-dpng', '-r0');
%% Plot Comparison Heatmap
figure('units','normalized','position',[0 0 1 1])
colormap jet
csvname1=sprintf('Synchrony_postpulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
csvname2=sprintf('Synchrony_prepulse_zoom_state%d_probii%1.0f_std%1.0f_num%dto%d.csv', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
compare=csvread(csvname1)-csvread(csvname2);
subaxis(1,2,1, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingLeft', 0.07, 'PaddingRight', 0.01);
pcolor(compare)
caxis([-.5 1])
colorbar
xlabels=0.25:.5:3;
ylabels=150:20:400;
set(gca,'TickDir','out')
set(gca,'box','off')
set(gca, 'XTick', 1.5:2:12.5);
set(gca, 'XTickLabel', xlabels);
set(gca, 'YTick', 1.5:4:51.5);
set(gca, 'YTickLabel', ylabels);
xtickangle(45)
ytickangle(45)
set(gca, 'FontSize', 20);
% ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
ylabel('External Applied Current (pA)', 'FontSize', 26)
title('Synchrony Measure: Post-Pre', 'FontSize', 30);
% subaxis(1,2,2, 'Spacing', 0.01, 'Padding', 0.05, 'Margin', 0.05, 'PaddingBottom', 0.12, 'PaddingTop', 0.075, 'PaddingRight', 0.01, 'PaddingLeft', 0.05);
% pcolor(popfreq_full)
% caxis([0 200])
% colorbar
%
% set(gca,'TickDir','out')
% set(gca,'box','off')
% set(gca, 'XTick', 1.5:2:20.5);
% set(gca, 'XTickLabel', xlabels);
% set(gca, 'YTick', []);
% set(gca, 'YTickLabel', ylabels);
% xtickangle(45)
% ytickangle(45)
% set(gca, 'FontSize', 20);
% % ylabel({'Inter-connectivity Density'; 'Compared to E-E Density'}, 'FontSize', 26)
% % xlabel('Inhibitory Synaptic Weight (nS)', 'FontSize', 26)
% % ylabel('External Applied Current (pA)', 'FontSize', 26)
% title('Mean Firing Frequency (Hz)', 'FontSize', 30);
supAxis=[.0750 .10 .85 .85];
str1= sprintf('Inhibitory Synaptic Weight (nS)');
str3= sprintf('Connectivity Density: %1.2f; State: %1.0f; Pre-Pulse', variables(1,1), variables(1,5));
[ax,h]=suplabel(str1, 'x', supAxis);
set(h, 'FontSize', 26);
[ax3,h3]=suplabel(str3, 't', supAxis);
set(h3, 'FontSize', 20);
str1=sprintf('Zoom_compare_state%d_probii%1.0f_std%1.0f_num%dto%d.png', variables(1,5), variables(1,1)*100, variables(1,4), brange(1),brange(end));
% saveas(gcf, str1)
set(gcf,'PaperPositionMode','auto')
print(str1, '-dpng', '-r0');
end