// genesis // Setting the axonal propagation velocity float CABLE_VEL = 1 // scale factor = 1/(cable velocity) sec/meter //float destlim = {P23RSd_P6RSc_destlim} float destlim = 1.0 // being lazy; should calculate based on model size instead /* * Usage : * volumeconnect source-path destination-path * [-relative] * [-sourcemask {box,ellipse} x1 y1 x2 y2] * [-sourcehole {box,ellipse} x1 y1 x2 y2] * [-destmask {box,ellipse} x1 y1 x2 y2] * [-desthole {box,ellipse} x1 y1 x2 y2] * [-probability p] */ //P23RSd - P6RSc AMPA str s //Load synapse location array str locations = "apdend3 apdend4 apdend5 apdend6 apdend7 apdend8 apdend9 apdend10" foreach s ({arglist {locations}}) barrierall //ayu rvolumeconnect /P23RSdnet/P23RSd[]/soma/spk4longrange \ /P6RScnet/P6RSc[]/{s}/Ex_ch13P23RSAMPA@{distantnodes} \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ -probability {{longrangeprobscale}*{P23RSd_P6RSc_prob}} //-probability 0.5 end //P23RSd - P6RSc NMDA str s //Load synapse location array str locations = "apdend3 apdend4 apdend5 apdend6 apdend7 apdend8 apdend9 apdend10" foreach s ({arglist {locations}}) barrierall //ayu rvolumeconnect /P23RSdnet/P23RSd[]/soma/spk4longrange \ /P6RScnet/P6RSc[]/{s}/Ex_ch13P23RSNMDA@{distantnodes} \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ -probability {{longrangeprobscale}*{P23RSd_P6RSc_prob}} end // For inhibitory long range connections ////P23RSd - P6RSc GABAa //str s ////Load synapse location array //str locations = "apdend3 apdend4 apdend5 apdend6 apdend7 apdend8 apdend9 apdend10" // //foreach s ({arglist {locations}}) // // barrierall //ayu // rvolumeconnect /P23RSdnet/P23RSd[]/soma/spk4longrange \ // /P6RScnet/P6RSc[]/{s}/Inh_ch13P23RSGABAa@{distantnodes} \ // -relative \ // -sourcemask box -1 -1 -1 1 1 1 \ // -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ // -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ // -probability {{longrangeprobscale}*{P23RSd_P6RSc_prob}} // //end // assigning delays barrierall //ayu rvolumedelay /P23RSdnet/P23RSd[]/soma/spk4longrange -radial {{P23RSd_P6RSc_axdelayCV}*{longrangeCVscale}} -add // assigning weights float P23RSdmaxweight = 1.0 float P23RSdminweight = 0.0 float P23RSddecayrate = 0.1 float longrangeweight = {longrangeweightscale}*{{{P23RSdmaxweight}-{P23RSdminweight}} * {exp {-1*{sqrt {{NX}^2*{SEPX}^2*{sqrtNnodesperregion}+{NY}^2*{SEPY}^2*{sqrtNnodesperregion}} }*P23RSddecayrate} } + {P23RSdminweight}} barrierall //ayu rvolumeweight /P23RSdnet/P23RSd[]/soma/spk4longrange -fixed {longrangeweight}