// genesis // Setting the axonal propagation velocity float CABLE_VEL = 1 // scale factor = 1/(cable velocity) sec/meter //float destlim = {P5RSa_P23FRBa_destlim} float destlim = 1.0 // being lazy; should calculate based on model size instead /* * Usage : * volumeconnect source-path destination-path * [-relative] * [-sourcemask {box,ellipse} x1 y1 x2 y2] * [-sourcehole {box,ellipse} x1 y1 x2 y2] * [-destmask {box,ellipse} x1 y1 x2 y2] * [-desthole {box,ellipse} x1 y1 x2 y2] * [-probability p] */ //P5RSa - P23FRBa AMPA str s //Load synapse location array str locations = "apdend3 apdend4aL apdend4bL apdend4aR apdend4bR apdend5aLLL apdend5aLL apdend5aLR apdend5aLRR apdend5aRRR apdend5aRR apdend5aRL apdend5aRLL" foreach s ({arglist {locations}}) barrierall //ayu rvolumeconnect /P5RSanet/P5RSa[]/soma/spk23longrange \ /P23FRBanet/P23FRBa[]/{s}/Ex_ch22P5RSAMPA@{distantnodes} \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ -probability {{longrangeprobscale}*{P5RSa_P23FRBa_prob}} //-probability 0.5 end //P5RSa - P23FRBa NMDA str s //Load synapse location array str locations = "apdend3 apdend4aL apdend4bL apdend4aR apdend4bR apdend5aLLL apdend5aLL apdend5aLR apdend5aLRR apdend5aRRR apdend5aRR apdend5aRL apdend5aRLL" foreach s ({arglist {locations}}) barrierall //ayu rvolumeconnect /P5RSanet/P5RSa[]/soma/spk23longrange \ /P23FRBanet/P23FRBa[]/{s}/Ex_ch22P5RSNMDA@{distantnodes} \ -relative \ -sourcemask box -1 -1 -1 1 1 1 \ -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ -probability {{longrangeprobscale}*{P5RSa_P23FRBa_prob}} end // For inhibitory long range connections ////P5RSa - P23FRBa GABAa //str s ////Load synapse location array //str locations = "apdend3 apdend4aL apdend4bL apdend4aR apdend4bR apdend5aLLL apdend5aLL apdend5aLR apdend5aLRR apdend5aRRR apdend5aRR apdend5aRL apdend5aRLL" // //foreach s ({arglist {locations}}) // // barrierall //ayu // rvolumeconnect /P5RSanet/P5RSa[]/soma/spk23longrange \ // /P23FRBanet/P23FRBa[]/{s}/Inh_ch22P5RSGABAa@{distantnodes} \ // -relative \ // -sourcemask box -1 -1 -1 1 1 1 \ // -destmask box -{destlim} -{destlim} -1 {destlim} {destlim} 1 \ // -desthole box -0.000001 -0.000001 -0.000001 0.000001 0.000001 0.000001 \ // -probability {{longrangeprobscale}*{P5RSa_P23FRBa_prob}} // //end // assigning delays barrierall //ayu rvolumedelay /P5RSanet/P5RSa[]/soma/spk23longrange -radial {{P5RSa_P23FRBa_axdelayCV}*{longrangeCVscale}} -add // assigning weights float P5RSamaxweight = 1.0 float P5RSaminweight = 0.0 float P5RSadecayrate = 0.1 float longrangeweight = {longrangeweightscale}*{{{P5RSamaxweight}-{P5RSaminweight}} * {exp {-1*{sqrt {{NX}^2*{SEPX}^2*{sqrtNnodesperregion}+{NY}^2*{SEPY}^2*{sqrtNnodesperregion}} }*P5RSadecayrate} } + {P5RSaminweight}} barrierall //ayu rvolumeweight /P5RSanet/P5RSa[]/soma/spk23longrange -fixed {longrangeweight}