<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <SDRun xmlns:xi="http://www.w3.org/2001/XInclude" xmlns="http://stochdiff.textensor.org"> <!-- this file defines a single run of the calculation, using morphology and reaction data brought in from other files --> <xi:include href="Rxn_SPNspineAChm4R_Gshydr5_AC1_GiGsfast-GapD.xml" /> <xi:include href="Morph_1sp2umDend.xml" /> <xi:include href="IC_SPNspineAChm4R_AC1_coupleGqhigh.xml" /> <xi:include href="Out_SPNspineCaMKII_DagL_AChm1R_AC1.xml" /> <xi:include href="StimCoupleTheta10hzAChNoRebound_DaDec1-15sITI.xml" /> <!--2D means the morphology is interpreted like a flatworm, 3D for roundworms. The 2D case is good for testing as it is eas/Stry to visualize the results (also, 3D may not work yet...) --> <geometry> 2D </geometry> <depth2D> 0.6 </depth2D> <distribution> BINOMIAL </distribution> <algorithm> INDEPENDENT </algorithm> <simulationSeed> 123 </simulationSeed> <outputQuantity>NUMBER</outputQuantity> <!-- run time for the calculation, milliseconds --> <runtime> 300000 </runtime> <!-- 100001 --> <!-- set the seed to get the same spines each time testing --> <spineSeed> 123 </spineSeed> <discretization> <!-- default largest size for elements in bulk volumes (dendrites), microns --> <defaultMaxElementSide>0.3</defaultMaxElementSide> <!-- discretization for spines, microns --> <spineDeltaX> 0.1 </spineDeltaX> <!-- This specifies the surface layers, first implemented in v.2.1.7 --> <surfaceLayers>0.1,0.2</surfaceLayers> <!-- override the default for a particular region. --> <!-- Matches against id or regionClass in the morphology file --> <!-- <MaxElementSide region="PSD">0.1</MaxElementSide> --> </discretization> <!-- timestep used in fixed step calculations, in milliseconds --> <fixedStepDt> 1 </fixedStepDt> <!-- interval at which stuff should be saved to the output file(s) --> <outputInterval> 500.0 </outputInterval> <!-- the tolerace is used for adaptive sims --> <tolerance> 0.002 </tolerance> <!-- calculation types include GRID_STEPPED_STOCHASTIC and GRID_STEPPED_CONTINUOUS for reaction-diffusion systems. Single mixed pool calculations should be listed here too (TODO) --> <!--calculation>GRID_STEPPED_STOCHASTIC</calculation--> <!--use the following for adaptive: --> <calculation>GRID_ADAPTIVE</calculation> </SDRun>