// Cholinergic Interneuron
//
// Josh Held, 7/2004
load_file("nrngui.hoc")
create soma, dend[2]
connect dend[0](0), soma(0)
connect dend[1](0), soma(1)
access soma
celsius = 22
forall Ra = 70
v_init = -55
soma {
L = 20
diam = 20
insert pas
g_pas = .001
e_pas = -55
insert na_ch
gbar_na_ch = 0.4
insert na2_ch
gbar_na2_ch = 1
insert kv2_ch
gbar_kv2_ch = .1
insert kv4_ch
gbar_kv4_ch = .4
insert kcnq_ch
gbar_kcnq_ch = .002
insert kir2_ch
gbar_kir2_ch = 0
insert bk_ch
gbar_bk_ch = 1
insert sk_ch
gbar_sk_ch = .003
insert hcn12_ch
gbar_hcn12_ch = 0
insert hcn2_ch
gbar_hcn2_ch = 0
insert cal_ch
gbar_cal_ch = .003
insert cap_ch
gbar_cap_ch = 5e-05
insert ca_ch // calcium handling
}
for i=0,1 {
dend[i] {
L = 200
diam = 2
insert pas
g_pas = .001
e_pas = -55
insert na_ch
gbar_na_ch = 0.1
insert na2_ch
gbar_na2_ch = 0.25
insert kv2_ch
gbar_kv2_ch = .1
insert kv4_ch
gbar_kv4_ch = .4
insert kcnq_ch
gbar_kcnq_ch = .0003
insert kir2_ch
gbar_kir2_ch = 0
insert bk_ch
gbar_bk_ch = 1
insert sk_ch
gbar_sk_ch = .003
insert hcn12_ch
gbar_hcn12_ch = .01
insert hcn2_ch
gbar_hcn2_ch = .03
insert cal_ch
gbar_cal_ch = .003
insert cap_ch
gbar_cap_ch = 0
insert ca_ch // calcium handling
}
}
load_file("graph.hoc")
load_file("changeval.hoc")
// A RunControl panel
xpanel("RunControl", 0)
v_init = -55
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 5
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 0
xvalue("t","t", 2 )
tstop = 5000
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.25
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 4
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 0
xvalue("Real Time","realtime", 0,"", 0, 1 )
xpanel(0,400)