TITLE HH_Kdr channel for LGMD
: Altered by RBD
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(S) = (siemens)
}
NEURON {
THREADSAFE
SUFFIX HH_Kdr
USEION k READ ek WRITE ik
: Range variables can differ across neuron (non constants) and their values are accessible
RANGE g, gmax, ntau, t1
GLOBAL vhalf
}
PARAMETER {
gmax= 0.008 (S/cm2)
vhalf=-38 (mV)
vn2=-60 (mV)
t1=75 (1)
t2=0.25 (ms)
tns=-9 (mV)
zn=9 (mV)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
ninf (1)
ntau (ms)
g (S/cm2)
}
STATE {
n
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gmax*n^4
ik = g*(v-ek)
}
INITIAL {
settables(v)
n = ninf
}
DERIVATIVE states {
settables(v)
n' = (ninf - n)/(t1*ntau+t2)
}
:UNITSOFF
PROCEDURE settables(v (mV)) {
TABLE ninf, ntau DEPEND vhalf, zn, vn2, tns
FROM -80 TO 50 WITH 650
ninf = 1/(1 + exp((vhalf-v)/zn))
ntau = (1 (ms))/(1+exp((vn2-v)/tns))*ninf
}
:UNITSON