TITLE sEPSP
COMMENT
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sEPSP current model for summation analysis
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IMPLEMENTATION
This mechanism is implemented as a nonspecific current defined as a
point process, mimicking a current-clamp stimulation protocol, injecting
simulated EPSP I(t).
I = 0 for t < onset and
I(t) = A*(1 - exp(-1*(t-onset)/tau_r)) * (exp(1 - (t-onset) / tau_f))
for onset < t < offset
I = 0 for t > offset
PARAMETERS
This mechanism takes the following parameters:
A = 1.0 (nA) : current amplitude
taur = 0.3 (ms) : time constant of rise
tauf = 3.0 (ms) : time constant of fall
onset = 0.0 (ms) : start time of current
offset = onset+20 (ms) : end time of current
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ENDCOMMENT
NEURON {
POINT_PROCESS sEPSP
RANGE A, onset, taur, tauf
NONSPECIFIC_CURRENT i
}
UNITS {
(nA) = (nanoamp)
}
PARAMETER {
A = 0.0 (nA) : current amplitude.
taur = 0.3 (ms) : time constant of rise.
tauf = 3.0 (ms) : time constant of fall.
onset = 0.0 (ms) : start time of current
}
ASSIGNED {
i (nA) : injected current
}
BREAKPOINT {
if ((t < onset) || (t > onset+20)) {
i = 0
} else {
i = -A*(1 - exp(-1*(t-onset)/taur)) * (exp(1 - (t-onset) / tauf))
}
}