: Fast delayed rectifier
NEURON {
SUFFIX fKDR
USEION k WRITE ik
RANGE gbar, minf, mtau, i, g, m
GLOBAL erev, v0, taumult
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
erev = -85 (mV) : effective Ek
v0 = 23 (mV)
taumult = 1
gbar = 0 (S/cm2)
vmin = -100 (mV) : for look-up table
vmax = 100 (mV)
}
ASSIGNED {
v (mV)
i (mA/cm2)
ik (mA/cm2)
g (S/cm2)
malpha (/ms)
mbeta (/ms)
minf
mtau (ms)
}
STATE { m }
INITIAL {
rates(v)
m = minf
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gbar*m^4
ik = g*(v - erev)
i = ik
}
DERIVATIVE states {
rates(v)
m' = (minf - m)/mtau
}
PROCEDURE rates(v (mV)) {
TABLE minf, mtau
DEPEND taumult, v0
FROM vmin TO vmax WITH 199
malpha = 0.07*(v+v0)/(1-exp(-0.166*(v+v0)))
mbeta = 0.264*exp(-0.025*(v+48))
mtau = taumult/(malpha + mbeta)
minf = malpha/(malpha + mbeta)
}