//genesis //MScellSpine.g //This routine takes the MScell without synapses, and adds synapses include MScell/MScell.g //MScell without synapses include MScell/SynParamsTh.g //parameters on synaptic channels include MScell/channels/nmda_channel.g //function to make nmda channel, either GHK or not, in library include MScell/channels/synaptic_channel.g // function to make non nmda synaptic channels in library include MScell/AddSynapticChannels.g // contains functions to add channels to compartments include MScell/spines.g //creates spines, puts channels & calcium in spines function make_MS_cell_spine (cellname,pfile) str cellname,pfile str CompName make_MS_cell {cellname} {pfile} //************* create synaptic channels in library ********* pushe /library make_synaptic_channel {AMPAname} {AMPAtau1} {AMPAtau2} {AMPAgmax} {EkAMPA} make_NMDA_channel {NMDAname} {EkNMDA} {Kmg} {NMDAtau2} {NMDAgmax} {ghk_yesno} make_synaptic_channel {GABAname} {GABAtau1} {GABAtau2} {GABAgmax} {EkGABA} make_spines pope {cellname} //********************* end synaptic channels in library ************** //**************SPINES*************************/ /* these functions needs to be modified. The following 3 should be optional 1. allow for putting synaptic channels on spines in library 2. use new calcium functions and optionally create such in spine 3. possibly vdep channels in the spines */ //add_spines_evenly {cellname} spine 310.0e-6 320.0e-6 0.1 //distal for thal. proximal for cortex add_spines_evenly {cellname} spine 60.0e-6 320.0e-6 0.1 end