: Kv1 channel
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(S) = (siemens)
}
NEURON {
SUFFIX kv1
USEION k READ ek WRITE ik
RANGE gkbar, gk, ik
GLOBAL vhninf, kninf, antaul, bntaul, cntaul, dntaul, antaur, bntaur, cntaur,dntaur, brkvntau
}
PARAMETER{
gkbar = 0.006 (S/cm2)
ek = -88 (mV)
vhninf = -57
kninf = 11
antaul = 0
bntaul = 4.59
cntaul = -56
dntaul = 15.4
brkvntau = -60
antaur = 0.21
bntaur = 5.6
cntaur = -96
dntaur = 19.6
}
ASSIGNED{
v (mV)
ik (mA/cm2)
gk (S/cm2)
ninf
ntau (ms)
}
STATE{
n
}
BREAKPOINT{
SOLVE states METHOD cnexp
gk = gkbar * n^4
ik = gk * (v - ek)
}
UNITSOFF
INITIAL{
settables(v)
n = ninf
}
DERIVATIVE states{
settables(v)
n' = (ninf-n)/ntau
}
PROCEDURE settables(v (mV)){
TABLE ninf, ntau
FROM -100 TO 100 WITH 200
ninf = 1/(1+exp(-(v-vhninf)/kninf))
if (v < brkvntau){
ntau = antaul+bntaul*(1/(1+exp(-(v-cntaul)/dntaul)))
}else{
ntau = antaur+bntaur*(1/(1+exp((v-cntaur)/dntaur)))
}
}
UNITSON