: Kv2 channel
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(S) = (siemens)
}
NEURON {
SUFFIX kv2
USEION k READ ek WRITE ik
RANGE gkbar, gk, ik
GLOBAL vhninf, kninf, antaul, bntaul, cntaul, dntaul, antaur, bntaur, cntaur,dntaur,brkvntau
}
PARAMETER{
gkbar = 0.012 (S/cm2)
ek = -88 (mV)
vhninf = -32
kninf = 8.6
antaul = 15
bntaul = 53.1
cntaul = -46.3
dntaul = 14
brkvntau = -30
antaur = 0.75
bntaur = 23
cntaur = -25.6
dntaur = 4.6
}
ASSIGNED{
v (mV)
ik (mA/cm2)
gk (S/cm2)
ninf
ntau (ms)
}
STATE{
n
}
BREAKPOINT{
SOLVE states METHOD cnexp
gk = gkbar * n^4
ik = gk * (v - ek)
}
UNITSOFF
INITIAL{
settables(v)
n = ninf
}
DERIVATIVE states{
settables(v)
n' = (ninf-n)/ntau
}
PROCEDURE settables(v (mV)){
TABLE ninf, ntau
FROM -100 TO 100 WITH 200
ninf = 1/(1+exp(-((v-vhninf)/kninf)))
if (v < brkvntau){
ntau = antaul+bntaul*(1/(1+exp(-(v-cntaul)/dntaul)))
}else{
ntau = antaur+bntaur*(1/(1+exp((v-cntaur)/dntaur)))
}
}
UNITSON