: Kv3 channel
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(S) = (siemens)
}
NEURON {
SUFFIX kv3
USEION k READ ek WRITE ik
RANGE gkbar, gk, ik
GLOBAL vhninf, kninf, antaul, bntaul, cntaul, dntaul, antaur, bntaur, cntaur,dntaur, brkvntau
}
PARAMETER{
gkbar = 0.004 (S/cm2)
ek = -88 (mV)
vhninf = -15
kninf = 8
antaul = 1
bntaul = 15
cntaul = -50
dntaul = 10
brkvntau = -20
antaur = 0.15
bntaur = 10
cntaur = -10
dntaur = 6
}
ASSIGNED{
v (mV)
ik (mA/cm2)
gk (S/cm2)
ninf
ntau (ms)
}
STATE{
n
}
BREAKPOINT{
SOLVE states METHOD cnexp
gk = gkbar * n^4
ik = gk * (v - ek)
}
UNITSOFF
INITIAL{
settables(v)
n = ninf
}
DERIVATIVE states{
settables(v)
n' = (ninf-n)/ntau
}
PROCEDURE settables(v (mV)){
TABLE ninf, ntau
FROM -100 TO 100 WITH 200
ninf = 1/(1+exp(-(v-vhninf)/kninf))
if (v < brkvntau){
ntau = antaul+bntaul*exp(-((v-cntaul)/dntaul)^2)
}else{
ntau = antaur+bntaur*(1/(1+exp((v-cntaur)/dntaur)))
}
}
UNITSON